Protein Alignment CATSPER2 and slc9a2

DIOPT Version :9

• Sequence 1: NP_001269239.1
• Gene: CATSPER2 / 117155
• HGNCID: 18810
• Length: 534
• Species: Homo sapiens
• Sequence 2: XP_004911848.1
• Gene: slc9a2 / 101732511
• XenbaseID: XB-GENEPAGE-22069121
• Length: 791
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 97/519 - (18%)
• Similarity: 183/519 - (35%)
• Gaps: 196/519 - (37%)

Human   110 VLECPLFKNFI-------IFLVFLNT-------IILMVEIELLESTNTKLWPL------KLTLE- 153
            :|:|.||.:.|       :..||.|.       |::..|..|.::....|:.|      ..|:|
 Frog   193 LLQCLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCEMKTIET 257

Human   154 ------VAAWFILLI--FILEILLKWLSNFSVFWKSAWNV----FDFVVTMLS-LLPEVVVLVGV 205
                  :|..|::.|  |.:.|:..:::.|:..:.....|    |.|:.:.|| |..|:..|.|:
 Frog   258 SDVFSGIAILFLVGIGGFFIGIIFGFVAAFTTRFTRNIRVIEPLFVFLYSYLSYLTAEMFHLSGI 322

Human   206 TGQSVWLQLLRICRVLRSLKLLAQ-------FRQIQIIILVLVRALKSMTFLLM----------- 252
            ..       :..|.|  |:|...:       :..|:..:.:|....:::.|:.|
 Frog   323 VA-------ITTCAV--SMKKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGQNHEW 378

Human   253 -----LLLIFFYIF-AVTGVYVFSEYTRSPRQDLEYHVFFSDLPNSLVTVFILFTLDHWYALLQD 311
                 ...:||.:| ...||::.::...          ||..:|.::...||:.     |..|:
 Frog   379 NWAFVCFTLFFCLFWRAAGVFILTQLIN----------FFRTIPLTMKDQFIIA-----YGGLR- 427

Human   312 VWKVPEVSRIFSSIYFILWLLLGSIIF-------RSIIVAMMVT------------NFQNIRKE- 356
                       .:|.|.|..||...:|       .::||.:..|            .|.|:::.
 Frog   428 -----------GAICFALVFLLPDSVFPRKNLFITAVIVVIFFTVFIQGITIRPLVEFLNVKRAD 481

Human   357 -----LNEEMARREV-QLKA---------------DMFKR---QIIQR---RKNMSHEALTSSHS 394
                 ::||:..|.: .:||               |.||:   :.:::   ::|....::.|.:.
 Frog   482 KKQQIISEEIHSRFLDHVKAGVEDICGHWGHNYCKDKFKKFDEKFLRKLLIKENEPTSSIVSLYK 546

Human   395 KIEDRGASQQRE---SLD--LSEVSEVESN----YGATE----EDLI------------------ 428
            |:|.:.|.:..|   |.|  ||.:|..|..    ...||    .|::
 Frog   547 KLEIKQAIEMAETGLSRDPSLSSLSTYEKQKVKPLSPTEVNDMRDMLTKNLYQIRQRTLSYNRHN 611

Human   429 ----TSASKTEETLSKKREYQSSSCVSSTSSSYSSSSESRFSESIGRLDWETLVHE----NLPG 484
                ||..:.:|.|.::|.....|...|:.:|..:::                ||:    :|||
 Frog   612 LAGGTSEKQAKEILIRRRHSMRESLKKSSLNSRRAAT----------------VHQARYLSLPG 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CATSPER2	NP_001269239.1	Ion_trans	178..356	CDD:278921	40/225 (18%)
slc9a2	XP_004911848.1	b_cpa1	63..618	CDD:273294	85/460 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900