DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptf1a and Fer1

DIOPT Version :9

Sequence 1:	NP_446416.1	Gene:	Ptf1a / 117034	RGDID:	621709	Length:	326	Species:	Rattus norvegicus
Sequence 2:	NP_001262334.1	Gene:	Fer1 / 2768661	FlyBaseID:	FBgn0037475	Length:	256	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	75/173 - (43%)
Similarity:	96/173 - (55%)	Gaps:	43/173 - (24%)

- Green bases have known domain annotations that are detailed below.

  Rat   148 ARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYIN 212
            :.:.||::..:::.|.|||||:||||||||||:||||||:|||||||||||||||||:|||.||.
  Fly    72 SHKPRRLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYIT 136

  Rat   213 FLSELVQADLPLRGSGTGGCGGPGGSRHLGGDSPGNQAQ---------KVIICHRGTRSPSPSDP 268
            ||||:|:.|                   ..|:.||...|         |:|:          .|.
  Fly   137 FLSEMVKKD-------------------KNGNEPGLSLQRNYQKEPPKKIIL----------KDR 172

  Rat   269 DYGLPPLAGHSLSWADEKQLKEQNIIRTAKVWTPEDPRKLNSK 311
            ..|:    .|||||. .|..:.......|:.|||||||..:|:
  Fly   173 TGGV----AHSLSWY-RKGDRYPGSKLYARTWTPEDPRGPHSQ 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptf1a	NP_446416.1	bHLH_TS_PTF1A	164..218	CDD:381423	47/53 (89%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	229..249		3/19 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	304..326		4/8 (50%)
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	44/51 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340734
Domainoid	1	1.000	94	1.000	Domainoid score	I7308
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I4724
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1269550at2759
OrthoFinder	1	1.000	-	-		FOG0008172
OrthoInspector	1	1.000	-	-		oto98244
orthoMCL	1	0.900	-	-		OOG6_108748
Panther	1	1.100	-	-	LDO	PTHR23349
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6136
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760