|
Human 1 MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVIN 65
|||||:||||.|||||||||||||||||.|||||||||:|||||||||||.:.||||||:|:..|
Frog 44 MAAFGILSYEHRPLKRPRLGPPDVYPQDAKQKEDELTALNVKQGFNNQPAVSADEHGSAKNVNFN 108
Human 66 PSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLSILA 130
|:||.:.||||::|||:.||..|||::|||||.|||:.|||.|:||:|::|||||||.|||:.||
Frog 109 PAKISSNFSSIMSEKLRCNTLPDTGRRKPQVNQKDNFMLVTVRTQSSINTWFSDLAGTKPLTHLA 173
Human 131 KKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYL 195
|||||..|||:||.:||::|||::||.||||||||||:||:|.|:|||...||.:|||||.||||
Frog 174 KKVPIFGKKEEVFGFLARFSVPVMRAAWLIKMTCAYYAAITETKVKKRHVMDPIIEWTQIITRYL 238
Human 196 REQLAKISDFYHMASSTGDGPV-PVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVL 259
.|||.||:|:|..|......|. |:|||||.|:||||||||||..|||:|||::||:|||:|:..
Frog 239 WEQLQKIADYYRPALGGCSSPSGPMPPEVEVALKQWEYNEKLALFMFQDGMLDRHEFLTWVLECF 303
Human 260 EKIRPMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMMIGP 324
||||..:|:||||||||:|:||:..||||||||||||||.|||:.||..| .:|..|:|...
Frog 304 EKIRQGEDELLKLLLPLLLRYSNSLVQSAYLSRRLAYFCTRRLAQLLEGS----GSHPGHLMTAQ 364
Human 325 NNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENK 389
..::: .|:|.||.|..|.....|||.|.|.||.|||:|||||||::.|||||||||:||..:|:
Frog 365 TGTAL-PPAPAPPPPSGSAPSSPFSDLLQCPQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDNR 428
Human 390 SANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGV 454
...|||||.|.:||||||||||::||.||||.::.::|||||:|||:||||||||||||:|||.
Frog 429 -IKTGSPLDHLPIAPSSLPMPGGSSAFTQQVRRKLRDMEQQIKERGRSVEVRWSFDKCQEATAGF 492
Human 455 TISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKR 519
.|.||||||||||.|.|:::|.||::::||::||.....||..|::|:|:|||||||||||||||
Frog 493 PIGRVLHTLEVLDSHSFEKSDFSNNLDSLYNRIFGLGLGKDGHEISPDDDAVVTLLCEWAVSCKR 557
Human 520 SGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSSSLAG-SSLPVFQNVLLRFLDTQAPS 583
.|.|||:.||||||||||||||||||:||.:|||.|:||.||:. |:.||||.|||:|||||||.
Frog 558 YGHHRALVVAKLLEKRQAEIEAERCGDSEAVDEKGSVSSGSLSALSAPPVFQEVLLQFLDTQAPM 622
Human 584 LSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTA-STRPRSPVGENADEHY 647
|:||.:|.|:|||.||||||||.||||||||:.|||||||||||.:.. :.|||||..:.:|:..
Frog 623 LTDPANESERVEFYNLVLLFCELIRHDVFSHNMYMCTLISRGDLGIDPHAPRPRSPYEDPSDDTD 687
Human 648 SKDHD----VKMEEQSIMAHMGIDSGTTNIFDEVDKSDFKTDFGSEFPIFSP-------MPGESC 701
.|:.: :|:|:.::...|.||.|:..:|::::| ||||:||| .||.
Frog 688 RKEGEANSSIKLEDTTLSETMDIDHGSGALFEDMEK--------SEFPMFSPAMRCEGRSPGP-- 742
Human 702 ENANTSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLY 766
|:.:..:.|.: |.:..|.|...: ||..||:|||||||||.:||.|||||||.::||
Frog 743 EDGDRDIRRTV-----KGLNGEGPLSAL----YDQPRHIQYATHFPIPQEESCSHECNQRLVVLY 798
Human 767 GVGKERDEARHQLKKITKDILKILNKKSTTETG----VG---------------------DEGQK 806
|||::||:|||.:|:||:||||:||:|||:||| :| ||||:
Frog 799 GVGRQRDDARHIIKRITRDILKVLNRKSTSETGKVVVMGKVKQIEKQVNVPKLTLSPCGTDEGQR 863
Human 807 ARKNKQETFPTLETVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDL 871
.|:.|.|.|||.|.:|.:.|.||:|||||||:|:|.||||||||||.|.||||||..|||.||||
Frog 864 RRRAKPEAFPTAEEIFCRFQQLSHFDQHQVTAQVSRNVLEQITSFALGLSYHLPLVQHIQFIFDL 928
Human 872 MEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQT 936
||.:|||:|||||||||||||||||||||||||||.||||.|||:|||||||.||:|||||.:||
Frog 929 MEYSLNISGLIDFAIQLLNELSVVEAELLLKSSSLVGSYTMGLCLCIVAVLRHYHTCLILNQEQT 993
Human 937 AQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVM 1001
|||||||||||||.:|.|:.||.||||||||||||.|||||:||||:|||..|||||.|||.||.
Frog 994 AQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVE 1058
Human 1002 PANSNLRWDPDFMMDFIENPSARSINYSMLGKILSDNAANRYSFVCNTLMNVCMGHQDAGRINDI 1066
|::||:.|:.:||:|.|.|||..|:|..||||:|||:..||||||||.|::||.|..|..|:|||
Frog 1059 PSDSNMLWEQEFMLDTIINPSGHSVNCGMLGKLLSDSPTNRYSFVCNALVHVCAGDHDTDRVNDI 1123
Human 1067 ANFSSELTACCTVLSSEWLGVLKALCCSSNH-VWGFNDVLCTVDVSDLSFHDSLATFIAILIARQ 1130
|...:|||..|..|||||||||||||||||: ..||||:||.|||||||||||||||:|||:|||
Frog 1124 AILCAELTGSCKALSSEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILVARQ 1188
Human 1131 CFSLEDVVQHVALPSLLAAACGDADAEPGARMTCRLLLHLFRAPQACFLPQATGKPFPGIRSSCD 1195
|..|||:::..|:||||.|||.:.|:|.|||:|||:|||||:.||.........||..|||||||
Frog 1189 CLLLEDLIRCAAIPSLLNAACSEQDSEAGARLTCRILLHLFKTPQLNPCEPDGSKPTVGIRSSCD 1253
Human 1196 RHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNP 1260
||||||:.|.|..|||||||||:.:||||::..:..|.....| :.:.:||.|.
Frog 1254 RHLLAASQNRIVDGAVFAVLKAVFVLGDAELRGSGFSHPTGTD--------NASEEDIATR---- 1306
Human 1261 KSCGKSISIETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQL 1325
::.|:.:|||||:|.|||:||||:|||||||||.|::. ||.|...:.|||||:.|||:|:||
Frog 1307 RAGGRPVSIETASLDEYAKYVLRSICQQEWVGERCVRS---LCEDSNDLQDPVLSSAQAQRLMQL 1368
Human 1326 ICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDN 1390
|||||.:.:..:|||.|||.||.|||||:|||:|||.||||||||| .|.: |||:||:|
Frog 1369 ICYPHRLNDTEQGDNPQRQRIKHILQNLDQWTMRQSALELQLMIKQ---TPSN----EMNSLLEN 1426
Human 1391 IAKATIEVFQQSADLNNSSNSGMSLFNPNSIGSADTSSTRQNG-IKTFLSSSERRGVWLVAPLIA 1454
|||||||||||||: |:..:..|..::.:|.:|:...|. .|..|||.||.|.||||||||
Frog 1427 IAKATIEVFQQSAE-----NACAAPANSAALSNATSSNAPPNSKTKPVLSSLERSGAWLVAPLIA 1486
Human 1455 RLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREG 1519
:|||||||.|||||||||||||||||||:||||||||||||||||||||||||||||||||||||
Frog 1487 KLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREG 1551
Human 1520 LLTSLQNQVNQILSNWREERYQDDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQ 1584
|||||..||.||:|||||::||||.|..|::|:.|:||||||||||||||||||.||:||:|||.
Frog 1552 LLTSLYGQVQQIVSNWREDQYQDDCKTPQLLHDVLKLRLNLVGGMFDTVQRSTQQTTEWAVLLLD 1616
Human 1585 IITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKR 1649
||:||||||.:||||||||||||.||||||||:|:|:.|.|..||||||||||||||:|||||::
Frog 1617 IISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQ 1681
Human 1650 SESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEG 1714
|||::||||||||||||.|||||||.|||||||||||||||||.||:|||||||||:||||||||
Frog 1682 SESLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEG 1746
Human 1715 QKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHPMPKPRSYYLQPLPLPPEEEEEEPTSPVS 1779
.|..|||||.|||||||||||.:.|||..|||||||..||||||||:.||||| |:|||.:|.|
Frog 1747 IKQSAPLSWGWFGTVRVDRRVSRMEEQQRLLLYHTHLKPKPRSYYLENLPLPP--EDEEPPTPTS 1809
Human 1780 QEPERKSAEL--SDQ----GKTTTDEEK---KTKGRKRKTKSSSRVDEYPQSNIYRVPPNYSPIS 1835
.||::|.:|. .|: |.|.||:.| |.|..|::..:.|:|:|:|... ..|..|..:.
Frog 1810 TEPDKKLSEALKVDKSGVGGTTNTDDRKKPSKPKREKKRNMAPSKVEEFPLGP--GRPGPYGMVP 1872
Human 1836 SQMMHHPQSTLWGYNLVGQPQQP----GFFLQNQSLTPGGSRLDPAGSFVPTNTKQAL------- 1889
:.::| ....|..:.| ..:.|||.|.|||.||| .|:.| |:.|:
Frog 1873 TDLLH--------TQAAGMSRLPYATQNMYAQNQPLPPGGPRLD--NSYRP--TRMAMVKVPARP 1925
Human 1890 --------SNMLQRRSGAMMQPPSLHAITSQQQLIQMKLLQQQQQQRLLRQAQTRPFQQDFCNSA 1946
:.|:......|.:| |..:.|.:||:||.|.:|.:
Frog 1926 QYVSGVPQAGMMDSYKPVMYRP--------QPPIPQGQLLRQQLQAKLAQ--------------- 1967
Human 1947 VSLLEDFDNIMGQPGDQAALFAAQARPSPQLPQYPGLQQAQTMPQGYTMYGTQMPLQQ-TSQQQA 2010
.:|.|| .|...|.|.|..:| |||||.||:.|.||| ....||
Frog 1968 --------GMMPQP----------VRQMSQTPSYGSMQ-----PQGYTSYGSHMTLQQHPPPSQA 2009
Human 2011 GSVVLSPSYNSRAYPAA--HSNPVLMERLRQIQQQPSGYVQQQASPYLQPLTGSQRLNHQALQQS 2073
|::| .|.|:::.||.: .|...|::.:||:||:|||||.||||.:....:..||..||.:.|:
Frog 2010 GALV-PPPYSTQQYPGSLPPSGGALLDPVRQMQQRPSGYVHQQASGFSHSASAGQRFPHQQITQT 2073
Human 2074 ---PLVGGGIDAVLTSA-HPNLPSVPLPQDPMRPRQPQVRQQQRLLQMQQPQQPQ---------- 2124
|.:|......:|.| .|.| ||:...:.:|.|..:||::|:.||.||.|
Frog 2074 GMMPSMGHLTTQPVTGAIRPQL----LPEQQQQQQQQQYLRQQQILRQQQQQQQQQQQQQQQQQQ 2134
Human 2125 -----------------PQQPPQ-----PQQSSQSQSQTLGLQAMQPQQPLFPRQGLQQTQQQQQ 2167
||.||| ||..:|.|...||:|.:| |.||||||||||||
Frog 2135 QQQQQQQNQAPPQQQAPPQPPPQQVPTVPQPQTQGQPPGLGMQTLQ-----FQRQGLQQTQQQQQ 2194
Human 2168 TAALVRQLQKQLSSNQPQQGVTPYG 2192
|||||||||:||||.||||...|:|
Frog 2195 TAALVRQLQQQLSSTQPQQNSNPFG 2219
| 
