Protein Alignment Akt1 and JIL-1

DIOPT Version :10

• Sequence 1: NP_001159366.1
• Gene: Akt1 / 11651
• MGIID: 87986
• Length: 488
• Species: Mus musculus
• Sequence 2: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 133/338 - (39%)
• Similarity: 202/338 - (59%)
• Gaps: 17/338 - (5%)

Mouse   145 VTMNEFEYLKLLGKGTFGKVILVKEKA---TGRYYAMKILKKEVIVAKDEVA-HTLTENRVLQN- 204
            |::|:|:.:::||.|.:|:|.||::..   .|:.||||:|.|..:|.|.:.| ||.||..||:.
  Fly   256 VSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAI 320

Mouse   205 SRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKN 269
            .|:|||.:|.|:||:..:|..|:::|||||||.||.....|.|.|.|.|.||:|.||:.|| :..
  Fly   321 QRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLH-QLG 384

Mouse   270 VVYRDLKLENLMLDKDGHIKITDFGLCK-EGIKDGATMKTFCGTPEYLAPEVLEDNDYGR--AVD 331
            ::|||:||||::||.:|||.::||||.| ...::.....:||||.||:|||::.....|.  |||
  Fly   385 IIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVD 449

Mouse   332 WWGLGVVMYEMMCGRLPFYNQD----HEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRL 392
            ||.:||:.:|::.|..||...|    ..::...|..|:...|.:....|:..:..:|:|:|.:||
  Fly   450 WWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRL 514

Mouse   393 GGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQM----ITITPPD 453
            ||...||.||.:|.||..|.||::..|:...|:||.:|:|.|.:.|..|||.|:    ....||.
  Fly   515 GGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPS 579

Mouse   454 QVLLLSQWHSLRP 466
            ::.|...:..:.|
  Fly   580 RIRLFRGYTYVAP 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_001159366.1	PH_PKB	4..111	CDD:269947
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..137
		STKc_PKB	154..466	CDD:270723	129/327 (39%)
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	111/267 (42%)
		S_TK_X	532..591	CDD:214529	18/58 (31%)
		S_TKc	632..886	CDD:214567