Protein Alignment RAB39B and SEC4

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_116650.1
• Gene: SEC4 / 850543
• SGDID: S000001889
• Length: 215
• Species: Saccharomyces cerevisiae
• Alignment Length: 187
• Identity: 78/187 - (41%)
• Similarity: 118/187 - (63%)
• Gaps: 14/187 - (7%)

Human    10 RLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSI 74
            ::::||||.||||||:.||.|.:|......|:|:||..:.|:|. ||::|||:||||||||||:|
Yeast    22 KILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDIN-GKKVKLQLWDTAGQERFRTI 85

Human    75 TRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAE 139
            |.||||.::|.:|::|:|:.|:|.|:.:|.:....|... :...:|||:|.|::| |.||..:.|
Yeast    86 TTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHAND-EAQLLLVGNKSDMET-RVVTADQGE 148

Human   140 KLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELV-----------KRGEITIQEG 185
            .||...|:.:||:||::..||.:.|..|.:.|.|.:           |.|.|:|..|
Yeast   149 ALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVGNGKEGNISINSG 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	78/187 (42%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		12/15 (80%)
SEC4	NP_116650.1	Rab8_Rab10_Rab13_like	18..183	CDD:206659	72/163 (44%)