Protein Alignment RAB39B and Rab11

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 174
• Identity: 84/174 - (48%)
• Similarity: 116/174 - (66%)
• Gaps: 2/174 - (1%)

Human     7 YQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERF 71
            |.|::::||||.||||.|:.|||...|...|..|:||:|.:|.:|:: ||.||.||||||||||:
  Fly    10 YLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVD-GKTIKAQIWDTAGQERY 73

Human    72 RSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRH 136
            |:||.||||.:||.||::||....:::||..||.|.:.|.. ..||.:|||:|.||...|.|...
  Fly    74 RAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHAD-QNIVIMLVGNKSDLRHLRSVPTD 137

Human   137 EAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEI 180
            ||:..|...|:.:|||||.|:.|||.||.::..:||.:|.:.:|
  Fly   138 EAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQI 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	84/174 (48%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		2/7 (29%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		11/15 (73%)
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	80/164 (49%)