Protein Alignment RAB39B and Rab8

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Alignment Length: 165
• Identity: 79/165 - (47%)
• Similarity: 119/165 - (72%)
• Gaps: 2/165 - (1%)

Human     7 YQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERF 71
            |.|:|::||||.|||:|::.||:|..|......|:|:||..|.:|:: .|:||||||||||||||
  Fly     7 YLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELD-NKKIKLQIWDTAGQERF 70

Human    72 RSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRH 136
            |:||.||||.::|.:|::|||..:||:|:..|:...:.:... .:..:|:|:||:|..:|||::.
  Fly    71 RTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASA-DVEKMLLGNKCELTDKRQVSKE 134

Human   137 EAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDI 171
            ..|:||..||:|::||||:.:||||:||..|..||
  Fly   135 RGEQLAIEYGIKFMETSAKASINVEEAFLTLASDI 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	79/165 (48%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		12/15 (80%)
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	79/165 (48%)