Protein Alignment RAB39B and Rab3

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Alignment Length: 161
• Identity: 68/161 - (42%)
• Similarity: 107/161 - (66%)
• Gaps: 2/161 - (1%)

Human     7 YQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERF 71
            |.|:|::||:|:|||:..:.|:.:..|......|||:||..:.| ....||:||||||||||||:
  Fly    20 YMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV-FRHDKRVKLQIWDTAGQERY 83

Human    72 RSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRH 136
            |:||.||||.::|.:|::|:||..||.:|.:|:.:.|.:......| :|||:|||::.||.::..
  Fly    84 RTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQV-ILVGNKCDMEDQRVISFE 147

Human   137 EAEKLAAAYGMKYIETSARDAINVEKAFTDL 167
            ...:||...|:::.||||::.:||:..|..|
  Fly   148 RGRQLADQLGVEFFETSAKENVNVKAVFERL 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	68/161 (42%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		2/7 (29%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		11/15 (73%)
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	67/160 (42%)