Protein Alignment RAB39B and Rab2

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 188
• Identity: 91/188 - (48%)
• Similarity: 133/188 - (70%)
• Gaps: 2/188 - (1%)

Human     5 WLYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQE 69
            :.|.|:.|:|||:.||||||:.:||:.||..|.|.|:||:|.:|::.|: ||:||||||||||||
  Fly     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITID-GKQIKLQIWDTAGQE 66

Human    70 RFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVT 134
            .||||||:|||.:.|.||::|||.|.:|.::..|||:.:.|... .:|.:|:|:|.|||::|:|.
  Fly    67 AFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNS-NMVIMLIGNKSDLDSRREVK 130

Human   135 RHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQEGWEGVKSG 192
            :.|.|..|..:|:.::|||||.|.|||:||.:..::|||.::.|...|.....|:|.|
  Fly   131 KEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIG 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	91/186 (49%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		3/7 (43%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		12/15 (80%)
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	91/188 (48%)