Protein Alignment RAB39B and Rab14

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_788056.1
• Gene: Rab14 / 34840
• FlyBaseID: FBgn0015791
• Length: 239
• Species: Drosophila melanogaster
• Alignment Length: 208
• Identity: 85/208 - (40%)
• Similarity: 135/208 - (64%)
• Gaps: 3/208 - (1%)

Human     7 YQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERF 71
            |.|:.|:|||..||||||:.:|||.:|......|:||:|.:|::|:: .|:||||||||||||||
  Fly    34 YIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVD-DKKIKLQIWDTAGQERF 97

Human    72 RSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRH 136
            |::||:|||.:.|.|:::|||.|.::.::..||.:|:....|..::| |:|:|.||::.|:||..
  Fly    98 RAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIF-LIGNKSDLESTREVTYE 161

Human   137 EAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQEGWEGVK-SGFVPNVVHS 200
            ||::.|...|:.::|.||....|||:||.:..|.||:.::.|.:.:.....||: ....|:....
  Fly   162 EAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGVQHRPSQPSRTSL 226

Human   201 SEEVVKSERRCLC 213
            |.|...::.:|.|
  Fly   227 SSEATGAKDQCSC 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	84/206 (41%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		11/15 (73%)
Rab14	NP_788056.1	Rab14	34..199	CDD:133322	77/166 (46%)