Protein Alignment RAB39B and Rab6

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_477172.1
• Gene: Rab6 / 34636
• FlyBaseID: FBgn0015797
• Length: 208
• Species: Drosophila melanogaster
• Alignment Length: 159
• Identity: 61/159 - (38%)
• Similarity: 102/159 - (64%)
• Gaps: 2/159 - (1%)

Human     6 LYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQER 70
            |.:|:|:.:|:.:|||:.||.||....|......|:|:||.|:.:.:| .:.::||:||||||||
  Fly    10 LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLE-DRTVRLQLWDTAGQER 73

Human    71 FRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTR 135
            |||:..:|.|:|...::::||||..||....:|:::.:.. :...::.:|||:|.||..:|||:.
  Fly    74 FRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTE-RGSDVIIMLVGNKTDLSDKRQVST 137

Human   136 HEAEKLAAAYGMKYIETSARDAINVEKAF 164
            .|.|:.|....:.:|||||:...||::.|
  Fly   138 EEGERKAKELNVMFIETSAKAGYNVKQLF 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	60/158 (38%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		9/15 (60%)
Rab6	NP_477172.1	Rab6	13..173	CDD:206654	60/156 (38%)