Protein Alignment RAB39B and rab-39

DIOPT Version :10

• Sequence 1: NP_741995.1
• Gene: RAB39B / 116442
• HGNCID: 16499
• Length: 213
• Species: Homo sapiens
• Sequence 2: NP_495984.2
• Gene: rab-39 / 183941
• WormBaseID: WBGene00004286
• Length: 229
• Species: Caenorhabditis elegans
• Alignment Length: 206
• Identity: 110/206 - (53%)
• Similarity: 150/206 - (72%)
• Gaps: 8/206 - (3%)

Human     7 YQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERF 71
            ||:|||||||||||||.|:|.||||:.|::|||||||||::|::|:.||.|:|||:|||||||:|
 Worm    16 YQYRLIVIGDSTVGKSSLLRYFTEGKMAEISDPTVGVDFYARMIELRPGYRVKLQLWDTAGQEKF 80

Human    72 RSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHV---QPYQIVFVLVGHKCDLDTQRQV 133
            ||||::|||||||.|.::|.|||.||::|..|::|..:::   .|.:.||.|||.|.|:|:||||
 Worm    81 RSITKSYYRNSVGVLAIYDTTNRESFEHVENWVKEAALNLGGPSPSKCVFQLVGTKSDMDSQRQV 145

Human   134 TRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQEGWEGVKSGFVPNVV 198
            ...|.|..|..:.||:||||:|...||.:||..:.::|...|..||:...:||||:|:|     :
 Worm   146 NYEEGEYFAKYHKMKFIETSSRTGDNVNEAFHMIAQEIQNRVDDGELRPVDGWEGLKTG-----I 205

Human   199 HSSEEVVKSER 209
            ..|:.|..|||
 Worm   206 MRSQSVCLSER 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39B	NP_741995.1	Rab39	7..213	CDD:133311	110/206 (53%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..43		5/7 (71%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		12/15 (80%)
rab-39	NP_495984.2	Rab39	16..229	CDD:133311	110/206 (53%)