Protein Alignment NUS1 and nus1

DIOPT Version :10

• Sequence 1: NP_612468.1
• Gene: NUS1 / 116150
• HGNCID: 21042
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001016090.1
• Gene: nus1 / 548844
• XenbaseID: XB-GENE-981164
• Length: 218
• Species: Xenopus tropicalis
• Alignment Length: 209
• Identity: 135/209 - (64%)
• Similarity: 171/209 - (81%)
• Gaps: 4/209 - (1%)

Human    87 WRADGRSLEKLPVHMGLVITEVEQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDE 151
            |:|||..|.||||||.:::.|..|  |::|:|:||||||||||||:||||||||.|:::||||||
 Frog    12 WKADGCRLGKLPVHMAMLMGEEIQ--SYTDLANLVVWCMAVGISYVSVYDHQGILKQHSSRLMDE 74

Human   152 ILKQQQELLGLDCSKYSPEFAN-SNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQ 215
            :||||:||||.|.|||..|.:| :.|:.|:.|....:.|||:|||||..||:|||:|||||||:|
 Frog    75 VLKQQKELLGHDYSKYPLEHSNGTTDRVDRGLTHMPSFKVLAPEDGKMQIVKAAQNFCQLVAQEQ 139

Human   216 KRPTDLDVDTLASLL-SSNGCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFS 279
            ::|.::||:.|.||| ::...|||||:||||.||||||||||||||:||:|||||:|:.||||:|
 Frog   140 RKPIEMDVNALDSLLRTTQTFPDPDLILKFGSVDSTLGFLPWHIRLSEIISLPSHVNMRYEDFYS 204

Human   280 ALRQYAACEQRLGK 293
            .|..||||||||||
 Frog   205 VLSCYAACEQRLGK 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUS1	NP_612468.1	UppS	<196..293	CDD:439791	67/97 (69%)
		RXG motif, crucial for prenyltransferase activity. /evidence=ECO:0000269|PubMed:32817466, ECO:0000305|PubMed:28842490	290..292		1/1 (100%)
nus1	NP_001016090.1	Cis_IPPS	<123..217	CDD:469674	64/93 (69%)