Protein Alignment NUS1 and Nus1

DIOPT Version :10

• Sequence 1: NP_612468.1
• Gene: NUS1 / 116150
• HGNCID: 21042
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_084526.1
• Gene: Nus1 / 52014
• MGIID: 1196365
• Length: 297
• Species: Mus musculus
• Alignment Length: 297
• Identity: 265/297 - (89%)
• Similarity: 273/297 - (91%)
• Gaps: 4/297 - (1%)

Human     1 MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRN 65
            |||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||.|||||
Mouse     1 MTGLYELVWRVLHALLCLHLTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPRAVGRN 65

Human    66 RRHHRHPRG----GSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASLVVWCMA 126
            |||||||.|    |...||.|.|:|||||.|||:||||||||::||..|||||||||||||||||
Mouse    66 RRHHRHPHGGPGPGPGPAATHPRLRWRADVRSLQKLPVHMGLLVTEEVQEPSFSDIASLVVWCMA 130

Human   127 VGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQVLNCHLAVKVL 191
            |||||||||||||||||||||||||||||||||||.||||||.|||||||||||.|||..|||||
Mouse   131 VGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGQDCSKYSAEFANSNDKDDQDLNCPSAVKVL 195

Human   192 SPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKFGPVDSTLGFLPW 256
            ||||||||||||||||||||||:|::|||||||.|.|||||:|.|||||||||||||||||||||
Mouse   196 SPEDGKADIVRAAQDFCQLVAQQQRKPTDLDVDLLGSLLSSHGFPDPDLVLKFGPVDSTLGFLPW 260

Human   257 HIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK 293
            .||||||||||||||||||||||||||||||||||||
Mouse   261 QIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUS1	NP_612468.1	UppS	<196..293	CDD:439791	88/96 (92%)
		RXG motif, crucial for prenyltransferase activity. /evidence=ECO:0000269|PubMed:32817466, ECO:0000305|PubMed:28842490	290..292		1/1 (100%)
Nus1	NP_084526.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..86		14/22 (64%)
		UppS	<200..297	CDD:439791	88/96 (92%)
		RXG motif, crucial for prenyltransferase activity. /evidence=ECO:0000250|UniProtKB:Q96E22	294..296		1/1 (100%)