Protein Alignment NUS1 and nus1

DIOPT Version :10

• Sequence 1: NP_612468.1
• Gene: NUS1 / 116150
• HGNCID: 21042
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001002356.1
• Gene: nus1 / 436629
• ZFINID: ZDB-GENE-040718-48
• Length: 274
• Species: Danio rerio
• Alignment Length: 296
• Identity: 164/296 - (55%)
• Similarity: 208/296 - (70%)
• Gaps: 25/296 - (8%)

Human     1 MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRN 65
            |..|||:|||.|||||.|.|.:.:|.||..  |.|      :.|...:|.||        |:|.:
Zfish     1 MASLYEMVWRFLHALLYLQRAIVAWFRVHI--WRW------KLAVVDLLLPL--------ALGFH 49

Human    66 RRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASLVVWCMAVGIS 130
            .:....|:|    .....|:||.||||:|||||:|:||::|  |:|..::|||:|||||||||||
Zfish    50 NQKKTGPKG----TRTSRRVRWGADGRTLEKLPLHVGLLVT--EEEIHYTDIANLVVWCMAVGIS 108

Human   131 YISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFA--NSNDKDDQVLNCHLAVKVLSP 193
            |:||||:||:|||||||||:|||||||||||:..||||.|..  .:|.::.|||:|...||||||
Zfish   109 YVSVYDNQGVFKRNNSRLMEEILKQQQELLGMGSSKYSVEILKNGTNKQEHQVLSCQSMVKVLSP 173

Human   194 EDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLL-SSNGCPDPDLVLKFGPVDSTLGFLPWH 257
            :||:..||:|||..|:.|.||:|...|::|..|.||| .|...||||||||||.|.|||||||||
Zfish   174 DDGRLSIVQAAQQLCRAVEQKEKTSKDINVSVLDSLLKESKNIPDPDLVLKFGTVQSTLGFLPWH 238

Human   258 IRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK 293
            ||||||:|:|||::.||:|.:.||:::|.|||||||
Zfish   239 IRLTEIISMPSHIDASYDDLYDALQRFAGCEQRLGK 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUS1	NP_612468.1	UppS	<196..293	CDD:439791	59/97 (61%)
		RXG motif, crucial for prenyltransferase activity. /evidence=ECO:0000269|PubMed:32817466, ECO:0000305|PubMed:28842490	290..292		1/1 (100%)
nus1	NP_001002356.1	Cis_IPPS	75..273	CDD:469674	126/199 (63%)