Protein Alignment NUS1 and Nus1

DIOPT Version :10

• Sequence 1: NP_612468.1
• Gene: NUS1 / 116150
• HGNCID: 21042
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001157629.1
• Gene: Nus1 / 294400
• RGDID: 1307879
• Length: 293
• Species: Rattus norvegicus
• Alignment Length: 293
• Identity: 260/293 - (88%)
• Similarity: 269/293 - (91%)
• Gaps: 0/293 - (0%)

Human     1 MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRN 65
            |||||||||||||.|.||:|||||||||||||||||||||||||||||||||||||||.||||||
  Rat     1 MTGLYELVWRVLHLLFCLYRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKLPAVGRN 65

Human    66 RRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASLVVWCMAVGIS 130
            |||||||..|...||.|.|:|||||||||:||||||||||||..|||||||||||||||||||||
  Rat    66 RRHHRHPHRGPGPAATHPRLRWRADGRSLQKLPVHMGLVITEEVQEPSFSDIASLVVWCMAVGIS 130

Human   131 YISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQVLNCHLAVKVLSPED 195
            |||||||||||||||||||||||||||||||.||||||.|||||||||||||||..|||||||||
  Rat   131 YISVYDHQGIFKRNNSRLMDEILKQQQELLGQDCSKYSAEFANSNDKDDQVLNCPSAVKVLSPED 195

Human   196 GKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKFGPVDSTLGFLPWHIRL 260
            ||||||||||||||.|||:|:|||:|.|:.|.|||||:|.|||||||||||||||||||||.|||
  Rat   196 GKADIVRAAQDFCQSVAQQQRRPTELGVELLDSLLSSHGFPDPDLVLKFGPVDSTLGFLPWQIRL 260

Human   261 TEIVSLPSHLNISYEDFFSALRQYAACEQRLGK 293
            |||:|||||.||||||.||||||||||||||||
  Rat   261 TEIISLPSHSNISYEDLFSALRQYAACEQRLGK 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUS1	NP_612468.1	UppS	<196..293	CDD:439791	82/96 (85%)
		RXG motif, crucial for prenyltransferase activity. /evidence=ECO:0000269|PubMed:32817466, ECO:0000305|PubMed:28842490	290..292		1/1 (100%)
Nus1	NP_001157629.1	Cis_IPPS	95..292	CDD:469674	175/196 (89%)
		UppS	<196..293	CDD:439791	82/96 (85%)