Protein Alignment SLC22A12 and CG33233

DIOPT Version :9

• Sequence 1: XP_006718493.1
• Gene: SLC22A12 / 116085
• HGNCID: 17989
• Length: 578
• Species: Homo sapiens
• Sequence 2: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 89/470 - (18%)
• Similarity: 169/470 - (35%)
• Gaps: 122/470 - (25%)

Human   117 VDGWVYDRSIFTSTIVAKWNLV---CD---SHALKPMAQSIYLAGILVGAAACGPASDRFGRRLV 175
            |..::|..|: |.::.|.:.:|   |:   |...|.:..:..|.|::......|..:||:||:.|
  Fly    25 VSFFIYMYSV-TESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVASGLFIGFLADRYGRKFV 88

Human   176 LTWSYLQMAVMGTAAAFAPAFPVYCLFRFLL-AFAVAGVMMNTGTLRRSLTWRHAGGLHAGSRAE 239
            :..:.:........:|..|......:.|.:: .|..|...:..|.|         |..||
  Fly    89 IRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGFL---------GEFHA----- 139

Human   240 PLGLLAVMEWTAARARPLVMTL--NSLGFSFGHGLTAAVA-------------YGVRDWTLLQLV 289
                   ::|     ||:.:.:  .|.|.:..:....|:|             |.:|.|..|.:.
  Fly   140 -------IKW-----RPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMF 192

Human   290 VSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGK--GAVQDTLTPEVLLSAMRE- 351
            ..:|.:|..:....:.|:..:|::..|.|..|..|..:..:|.|  ..|..||:.|...:..:|
  Fly   193 FMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEEKSSTNDQEG 257

Human   352 ---------ELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLAL------DLQALGS 401
                     :|...:|..          .:|..|:..:  |...||..||.:      ::...||
  Fly   258 FWKTVWYEYKLLFSKPHV----------FKFFICLFLI--FGIFFTSIGLGIWFPVIRNMDNSGS 310

Human   402 N----------IFLLQ-------------------------MFIGVVDIPAKMGALLLLSHLGRR 431
            |          .|:..                         ::.|...|...:.|.:|:..:.|:
  Fly   311 NRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILASVLVHWMTRK 375

Human   432 PTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSEL---FPTVLRMTA 493
            ..:|..:|::.:..::..::......|...:.::.|.||     .|.:.:|.|   .|..||..|
  Fly   376 YVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPGV-----LIPLATSVLVDCLPVNLRGKA 435

Human   494 VGLGQMAARGGAILG 508
            :.:.:..||.|.:||
  Fly   436 LCMVRSLARFGGVLG 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A12	XP_006718493.1	2A0119	11..551	CDD:273328	89/470 (19%)
		MFS	122..541	CDD:119392	88/465 (19%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	89/470 (19%)
		MFS	23..>208	CDD:119392	40/209 (19%)
		MFS	354..>482	CDD:304372	23/102 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840