Protein Alignment CKMT1B and Argk2

DIOPT Version :10

• Sequence 1: XP_011519496.1
• Gene: CKMT1B / 1159
• HGNCID: 1995
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_648284.1
• Gene: Argk2 / 39040
• FlyBaseID: FBgn0035957
• Length: 388
• Species: Drosophila melanogaster
• Alignment Length: 348
• Identity: 143/348 - (41%)
• Similarity: 209/348 - (60%)
• Gaps: 23/348 - (6%)

Human    89 KHNNCMASHLTPAVYARLCDKTTPT-GWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADL 152
            |..:.:..|||..::.:|..||||: ..||..||.:|:.|  |.  ..||:.|.|.|.|:|||||
  Fly    50 KSKSLLKKHLTKEIFEKLKTKTTPSFNSTLLHCISSGMCN--HD--SGVGLYAPDPEAYKVFADL 110

Human   153 FDPVIQERHNGYDPRTMKHTTDLDASKIRSGYF------DERYVLSSRVRTGRSIRGLSLPPACT 211
            |||||:|.|     :..|.|....|:....|..      |..:::|:|||.||:::|....|..|
  Fly   111 FDPVIEEYH-----KCFKKTDKQPATAFGKGADFENLDPDGHFIVSTRVRCGRAVKGYPFNPCLT 170

Human   212 RAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWP 276
            .|:..|:|..:..|::.|.|:..|:|..|:.|.:..|:|||:||:|| |.....|.:||.:|.||
  Fly   171 EADYMELESKICGAVTSLTGEYKGKYMPLTGMDKCIQEQLIEDHYLF-KEGDRFLASAGASRYWP 234

Human   277 DARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERL 341
            ..|||:.|:.|:||:|.|||||.|:|||||||::.:|::|...|::.:.:.:|     |..:|||
  Fly   235 TGRGIFLNSAKNFLVWCNEEDHIRIISMEKGGDLGKVYDRMVGGVEALGKQLQ-----FNRDERL 294

Human   342 GYILTCPSNLGTGLRAGVHIKLP-LLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDR 405
            |::..||:||||.:||.|||||| |:.......|:.:..|||.|||.|..:.|.|||.||||..|
  Fly   295 GFLTFCPTNLGTSIRASVHIKLPNLMCDPDEMKKLADKYRLQIRGTSGEHSEAKGGVHDISNQRR 359

Human   406 LGKSEVELVQLVIDGVNYLIDCE 428
            :|.:|.|:::.:.||:..||:.|
  Fly   360 MGLTEYEIIKEMHDGIKGLIEAE 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CKMT1B	XP_011519496.1	creatine_kinase_like	80..437	CDD:153076	143/348 (41%)
Argk2	NP_648284.1	arginine_kinase_like	40..382	CDD:153079	142/346 (41%)