DRSC/TRiP Functional Genomics Resources

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Protein Alignment WDFY2 and Gga

DIOPT Version :10

Sequence 1:NP_443182.1 Gene:WDFY2 / 115825 HGNCID:20482 Length:400 Species:Homo sapiens
Sequence 2:NP_572571.1 Gene:Gga / 31902 FlyBaseID:FBgn0030141 Length:660 Species:Drosophila melanogaster


Alignment Length:77 Identity:18/77 - (23%)
Similarity:30/77 - (38%) Gaps:14/77 - (18%)


- Green bases have known domain annotations that are detailed below.


Human   326 SSKRSSIPLMGFEFEVRVCDSCHEAI---TDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTD 387
            :..:|..|:..|:||..|...|...:   ||.:..|...|..:.        ...:..||.:.|.
  Fly   571 AQNKSRQPVRDFQFEASVKKPCKVRLLTPTDSQMPPHKPFRPAT--------PINQVMLLLNPTG 627

Human   388 KVIKLWDMTPVV 399
            |.:   |:|.:|
  Fly   628 KAV---DVTCIV 636

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WDFY2NP_443182.1 WD40 <16..272 CDD:441893
WD 1 22..61
WD40 repeat 27..64 CDD:293791
WD 2 66..105
WD40 repeat 72..132 CDD:293791
WD 3 112..150
WD 4 153..192
WD40 repeat 159..197 CDD:293791
WD 5 197..236
WD40 repeat 203..240 CDD:293791
WD 6 240..279
WD40 repeat 245..283 CDD:293791
FYVE_WDFY1_like 279..348 CDD:277258 6/21 (29%)
WD40 repeat 321..363 CDD:293791 10/39 (26%)
WD 7 364..399 6/34 (18%)
WD40 repeat 369..395 CDD:293791 4/25 (16%)
GgaNP_572571.1 VHS_GGA_metazoan 8..144 CDD:340769
GAT_GGA_meta 201..283 CDD:410582
Alpha_adaptinC2 543..644 CDD:197886 18/77 (23%)
Blue background indicates that the domain is not in the aligned region.

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