Protein Alignment TBCB and alp11

DIOPT Version :10

• Sequence 1: NP_001272.2
• Gene: TBCB / 1155
• HGNCID: 1989
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_593683.2
• Gene: alp11 / 2542814
• PomBaseID: SPAC13D6.05
• Length: 234
• Species: Schizosaccharomyces pombe
• Alignment Length: 257
• Identity: 85/257 - (33%)
• Similarity: 135/257 - (52%)
• Gaps: 60/257 - (23%)

Human    11 VTVFISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVDDKFYSKLDQEDAL-- 73
            :|:||.||  :..:|:|.:...|:::.|.||..:||:|..             |.||..|.|.
pombe     4 ITLFIKSS--SANAERRINPQWTVSQLKTKLVPIVGTPEQ-------------YQKLTYEPASST 53

Human    74 ----------------------LGSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQ 116
                                  ||:..|:|....|:      || :::|:|:|:||.:.:|.|:.
pombe    54 VPGHVFTSEEENLDLGEFKLQPLGTIVVEDTRPPHL------RL-DFDDLSQVDKYVMPREQYEN 111

Human   117 RQDTVRSFLKRSKLGRYN---EEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGT 178
            |.|:|.::.||::|||:|   |..:|.::....:.|.:.:..     :.|||  .|||:  |.||
pombe   112 RTDSVYAWKKRNQLGRFNPDFEASKASRQESLKRELVDLQKN-----LNSRC--CAAGE--RYGT 167

Human   179 VMYVGLTD--FKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVTVGDFPEED 238
            :.|:||..  .....|:||.:|||:|||||:|:|||||..:.|:|:|::.:.|.|||||.||
pombe   168 IRYIGLVPEINNDNLWVGVEFDEPVGKNDGTVSGKRYFNAKNKHGSFLRSSEVEVGDFPPED 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBCB	NP_001272.2	Ubl_TBCB	11..89	CDD:340487	24/101 (24%)
		CAP_GLY	161..229	CDD:460154	32/69 (46%)
alp11	NP_593683.2	Ubl1_cv_Nsp3_N-like	4..83	CDD:475130	22/93 (24%)
		CAP_GLY	154..220	CDD:460154	32/69 (46%)