Protein Alignment TBCB and tbcb-1

DIOPT Version :10

• Sequence 1: NP_001272.2
• Gene: TBCB / 1155
• HGNCID: 1989
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_506367.1
• Gene: tbcb-1 / 186176
• WormBaseID: WBGene00009987
• Length: 229
• Species: Caenorhabditis elegans
• Alignment Length: 230
• Identity: 99/230 - (43%)
• Similarity: 139/230 - (60%)
• Gaps: 9/230 - (3%)

Human    15 ISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVDDKFYSKLDQEDALLGSYPV 79
            |:::...|..||:|...:::.:.|.||||:||:....|.::|:..||:...:|......|....|
 Worm     9 ITTNATDFPMEKKYPAGMSLNDLKKKLELVVGTTVDSMRIQLFDGDDQLKGELTDGAKSLKDLGV 73

Human    80 DDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAE 144
            .||.|||.:|.:|.. .:::|.|.||||.:|.:.|.:|.|:||::.|:.:    .|:..|.....
 Worm    74 RDGYRIHAVDVTGGN-EDFKDESMVEKYEMSDDTYGKRTDSVRAWKKKMQ----EEQGSAAPMEN 133

Human   145 AAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVN 209
            .:.:|.||.|:  :|.||:||||....|..|||.|.|||.|.||.|.|:||:||||:|||||||.
 Worm   134 ESDKLNEEAAK--NIMVGNRCEVTVGAQMARRGEVAYVGATKFKEGVWVGVKYDEPVGKNDGSVA 196

Human   210 GKRYFECQAKYGAFVKPAVVTVGDFPEEDYGLDEI 244
            |.|||:|..|||.||:|..|.||||||  ..:|||
 Worm   197 GVRYFDCDPKYGGFVRPVDVKVGDFPE--LSIDEI 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBCB	NP_001272.2	Ubl_TBCB	11..89	CDD:340487	24/73 (33%)
		CAP_GLY	161..229	CDD:460154	43/67 (64%)
tbcb-1	NP_506367.1	Ubiquitin_2	7..86	CDD:405277	25/76 (33%)
		CAP_GLY	148..216	CDD:460154	43/67 (64%)