Protein Alignment Adora3 and AdoR

DIOPT Version :9

• Sequence 1: NP_033761.2
• Gene: Adora3 / 11542
• MGIID: 104847
• Length: 319
• Species: Mus musculus
• Sequence 2: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Alignment Length: 368
• Identity: 111/368 - (30%)
• Similarity: 179/368 - (48%)
• Gaps: 68/368 - (18%)

Mouse     4 DNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTFYFIVSLALADIAVGVLVTP 68
            |:.:.:..|||.|...|..:.:.:::||:|||.|.:....||..|.|:|||||:||:.||.|..|
  Fly    32 DSDSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIP 96

Mouse    69 LAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVDRYLRVKLTVRY-RTVTTQRRIWLFL 132
            .||..|:.:..:.:||||...:|::....||..|:|::||||..:...:.| |.|.|:..|:: :
  Fly    97 FAILASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFI-I 160

Mouse   133 GLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVFFSFVTWILVPLVVMCVI 197
            .:||:...:||..|:|||:  |.:..:|.     |.|..|:..:|:||..|.| |:.|.::|...
  Fly   161 SMCWVAGTIVGFLPLFGWH--ADVNHNQE-----CLFVEVMDYNYLVFLYFAT-IITPALLMLAF 217

Mouse   198 YLDIFYII------------RNKLSQNLSG-----------------FRETRAFYGREFKTAKSL 233
            |..|:.:|            .:.||:..|.                 .|...|...|:.|..::|
  Fly   218 YTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNL 282

Mouse   234 FLVLFLFALCWLPLSIINFVSYFDVKIPD-------VAMCLGILLSHANSMMNPIVYACKIKKFK 291
            .:::..|.:||:||..||.:..|   .||       ...|  |:|||.||.:||::||..:|.|:
  Fly   283 SIIVLFFMICWIPLYTINCIKAF---CPDCYVHPKLTLFC--IILSHLNSAVNPVLYAYHLKDFR 342

Mouse   292 ---ETYFLILRALRLCQTSD--------------SLDSNMEQT 317
               :...|.:..:.:.|.::              |:||||..|
  Fly   343 AALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRST 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adora3	NP_033761.2	7tm_4	22..>128	CDD:304433	41/106 (39%)
		7tm_1	30..283	CDD:278431	93/289 (32%)
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	64/176 (36%)
		7tm_1	58..334	CDD:278431	93/289 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3630
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000536
OrthoInspector	1	1.000	-	-		otm42945
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24246
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.970