DRSC/TRiP Functional Genomics Resources

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Protein Alignment GBP5 and gbp1

DIOPT Version :9

Sequence 1:NP_001127958.1 Gene:GBP5 / 115362 HGNCID:19895 Length:586 Species:Homo sapiens
Sequence 2:NP_001016773.1 Gene:gbp1 / 549527 XenbaseID:XB-GENE-6045650 Length:595 Species:Xenopus tropicalis


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GBP5NP_001127958.1 GTPase domain (Globular). /evidence=ECO:0000250 1..309
NLRP3-binding. /evidence=ECO:0000269|PubMed:22461501 1..306
GBP 18..280 CDD:308078
GBP_C 282..574 CDD:308475
Required for tetramerization, but not for dimerization. /evidence=ECO:0000269|PubMed:22461501 529..586
gbp1NP_001016773.1 P-loop_NTPase 20..281 CDD:304359
GBP_C 283..579 CDD:202427
GBP_C 289..579 CDD:293879
coiled coil 549..560 CDD:293879
coiled coil 569..579 CDD:293879
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 345 1.000 Domainoid score I7575
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 596 1.000 Inparanoid score I6507
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1027269at2759
OrthoFinder 1 1.000 - - FOG0000238
OrthoInspector 1 1.000 - - otm54712
Panther 1 1.100 - - O PTHR10751
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X242
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
77.160

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