Sequence 1: | NP_001127958.1 | Gene: | GBP5 / 115362 | HGNCID: | 19895 | Length: | 586 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001287506.1 | Gene: | atl / 42934 | FlyBaseID: | FBgn0039213 | Length: | 541 | Species: | Drosophila melanogaster |
Alignment Length: | 467 | Identity: | 106/467 - (22%) |
---|---|---|---|
Similarity: | 189/467 - (40%) | Gaps: | 101/467 - (21%) |
- Green bases have known domain annotations that are detailed below.
Human 23 VNQEAL-EIL---SAITQPVVVVAIVGLYRTGKSYLM-----------------NKLAGKN---K 63
Human 64 GFSVASTVQSHTKGIWIW----CVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSS 124
Human 125 TFVYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEI 189
Human 190 DGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPD- 253
Human 254 ----DELEPEFVQQVTEFCSYIFSHSMTKTLPGGIM---VNGSRLKNLVL-----TYVNAISSGD 306
Human 307 LPCIENAVLALAQRENSAAVQKAIAHYDQQM-----GQKVQLPMETLQ-ELLDLHRTSEREAIEV 365
Human 366 FMKNSF--KDVDQSFQKELETLLDAKQNDICKRNLEASSDYCSA--------------LLKDIFG 414
Human 415 PLEEAVKQGIYS 426 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
GBP5 | NP_001127958.1 | GTPase domain (Globular). /evidence=ECO:0000250 | 1..309 | 75/326 (23%) | |
NLRP3-binding. /evidence=ECO:0000269|PubMed:22461501 | 1..306 | 74/323 (23%) | |||
GBP | 18..280 | CDD:308078 | 68/289 (24%) | ||
GBP_C | 282..574 | CDD:308475 | 37/175 (21%) | ||
Required for tetramerization, but not for dimerization. /evidence=ECO:0000269|PubMed:22461501 | 529..586 | ||||
atl | NP_001287506.1 | GBP | 14..289 | CDD:280433 | 69/297 (23%) |
MSC | <316..>471 | CDD:286487 | 32/142 (23%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165142061 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG2037 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D1027269at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.750 |