Sequence 1: | NP_001127958.1 | Gene: | GBP5 / 115362 | HGNCID: | 19895 | Length: | 586 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_588284.1 | Gene: | mto1 / 2539467 | PomBaseID: | SPCC417.07c | Length: | 1115 | Species: | Schizosaccharomyces pombe |
Alignment Length: | 566 | Identity: | 104/566 - (18%) |
---|---|---|---|
Similarity: | 229/566 - (40%) | Gaps: | 141/566 - (24%) |
- Green bases have known domain annotations that are detailed below.
Human 86 PNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYN----TVNKIDQGAIDLLHNVT 146
Human 147 ELTDLLKARNSPDLDRVEDPADSASFFPD---LVWTLRDFCLGLEID-----GQLVTPDEYLENS 203
Human 204 LRPKQGSDQRVQNFNLPRLC--IQKFFPKKKCFIFDLPAHQKKLAQLETLPDDELEPEFVQQVTE 266
Human 267 FCSYIFSHSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIENAVLALAQRENSAAVQKAIA 331
Human 332 HYDQ----------------------------QMGQKVQLPMETLQE--LLDLHRTSEREAIEVF 366
Human 367 MKNSF----KDVDQSFQKELETLLDAKQNDICKRNLEASS---DYCSALLKDIFGPLEEAVK-QG 423
Human 424 IYSKPGGHNLFIQKTEE-LKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQALTETEKKK 487
Human 488 KE-----AQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQM--EIAKQNWLAE------ 539
Human 540 ------QQKMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNN 579 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
GBP5 | NP_001127958.1 | GTPase domain (Globular). /evidence=ECO:0000250 | 1..309 | 43/236 (18%) | |
NLRP3-binding. /evidence=ECO:0000269|PubMed:22461501 | 1..306 | 42/233 (18%) | |||
GBP | 18..280 | CDD:308078 | 36/207 (17%) | ||
GBP_C | 282..574 | CDD:308475 | 66/349 (19%) | ||
Required for tetramerization, but not for dimerization. /evidence=ECO:0000269|PubMed:22461501 | 529..586 | 13/65 (20%) | |||
mto1 | NP_588284.1 | Cnn_1N | 252..319 | CDD:285263 | 15/84 (18%) |
Fib_alpha | 511..611 | CDD:285864 | 24/117 (21%) | ||
Mto2_bdg | 1052..1101 | CDD:289572 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
0 | 0.000 |