| Sequence 1: | NP_001127958.1 | Gene: | GBP5 / 115362 | HGNCID: | 19895 | Length: | 586 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_502809.2 | Gene: | atln-2 / 189829 | WormBaseID: | WBGene00012763 | Length: | 520 | Species: | Caenorhabditis elegans |
| Alignment Length: | 454 | Identity: | 94/454 - (20%) |
|---|---|---|---|
| Similarity: | 187/454 - (41%) | Gaps: | 77/454 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Human 6 HMSDPMCLIENFNEQ---LKVNQEALEIL----SAITQPVVVVAIVGLYRTGKSYLMN----KLA 59
Human 60 GKNK------------------GFSVASTVQSHTKGIWIWCVP----HPNWPNHTLVLLDTEGLG 102
Human 103 DVEKADNKNDIQ----IFALALLLSSTFVYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDRV 163
Human 164 EDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFF 228
Human 229 PKKKCFIFDLPAHQKKLAQLETLPD--DELEPEFVQQVTEFCSYIFS-HSMTKTLPGGIMVNGSR 290
Human 291 LKNLVLTYVNAISSGDLPCIENAVLALAQRENSAAVQKAIAHYDQQMGQKVQ-LPMETLQELLDL 354
Human 355 H---------------RTSEREAIEVFMKNSFKDVDQSFQKELETLLDAKQNDICKRNLEASSD 403 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| GBP5 | NP_001127958.1 | GTPase domain (Globular). /evidence=ECO:0000250 | 1..309 | 73/342 (21%) | |
| NLRP3-binding. /evidence=ECO:0000269|PubMed:22461501 | 1..306 | 72/339 (21%) | |||
| GBP | 18..280 | CDD:308078 | 66/301 (22%) | ||
| GBP_C | 282..574 | CDD:308475 | 25/138 (18%) | ||
| Required for tetramerization, but not for dimerization. /evidence=ECO:0000269|PubMed:22461501 | 529..586 | ||||
| atln-2 | NP_502809.2 | P-loop_NTPase | 41..310 | CDD:393306 | 64/288 (22%) |
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2037 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1027269at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||