DRSC/TRiP Functional Genomics Resources

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Protein Alignment CIRBP and NOP12

DIOPT Version :10

Sequence 1:NP_001287758.1 Gene:CIRBP / 1153 HGNCID:1982 Length:297 Species:Homo sapiens
Sequence 2:NP_014601.1 Gene:NOP12 / 854116 SGDID:S000005401 Length:459 Species:Saccharomyces cerevisiae


Alignment Length:168 Identity:41/168 - (24%)
Similarity:70/168 - (41%) Gaps:22/168 - (13%)


- Green bases have known domain annotations that are detailed below.


Human     8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSV 72
            :|||.|.|:..|:||.:.|...|.|..|.:::|.:|...:||.:|.|:::.....|:: :|.|.:
Yeast   281 IFVGNLDFEEIEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDLQSVNKALL-LNEKPM 344

Human    73 DGRQIR-------VDQAGKSSDNRSRGYRGGSAGGRGFFRGG--------RGRGRGFSRGGGDRG 122
            ..::..       ..:|.|...:|.:..:.|:..|.|..|.|        .||.:.. .|..||.
Yeast   345 KSQKQEDENTKKPTKKARKLRVSRCKNMKKGTTIGTGLDRNGLTDSQRTRAGRAKKI-LGKADRA 408

Human   123 YGGNR-----FESRSGGYGGSRDYYSSRSQSGGYSDRS 155
            ..|..     ..::.|...........||.:|..:.||
Yeast   409 TLGQEITIEGLRAKKGEGSTHLKKKKQRSATGRVTKRS 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CIRBPNP_001287758.1 RRM_CIRBP_RBM3 6..85 CDD:409883 22/83 (27%)
NOP12NP_014601.1 RRM1_Nop12p_like 148..272 CDD:410070
RRM2_Nop12p_like 280..370 CDD:410071 24/89 (27%)
Blue background indicates that the domain is not in the aligned region.

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