DRSC/TRiP Functional Genomics Resources

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Protein Alignment CIRBP and cirbpb

DIOPT Version :9

Sequence 1:NP_001287758.1 Gene:CIRBP / 1153 HGNCID:1982 Length:297 Species:Homo sapiens
Sequence 2:NP_001035411.2 Gene:cirbpb / 678563 ZFINID:ZDB-GENE-030131-5841 Length:206 Species:Danio rerio


Alignment Length:209 Identity:122/209 - (58%)
Similarity:136/209 - (65%) Gaps:45/209 - (21%)


- Green bases have known domain annotations that are detailed below.


Human     3 SDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
            |||||||:||||:||.|||||:.|||||.|::|.|::||||.||||||||||||.:||||||.||
Zfish     2 SDEGKLFIGGLSYDTTEQSLEEAFSKYGTIAKVDVIRDRETDRSRGFGFVTFENPEDAKDAMAAM 66

Human    68 NGKSVDGRQIRVDQAGKSSDNRSRGYRGGS-AGGRGFFRGGRGRG-------------RGF---- 114
            |||.||||.||||:||||. .||.|:|||| .||||||||.||||             |.|    
Zfish    67 NGKQVDGRMIRVDEAGKSG-GRSGGFRGGSRGGGRGFFRGSRGRGGGGYGGDRSYGSDRSFGGDR 130

Human   115 ------SRGGGDRGYGGNR----------------FESRSGGYGGSRDYYSSRSQSGGYSDRSSG 157
                  |.|||||||||..                :.:|||||.....|..:|:| ||| || ||
Zfish   131 SYGGDRSYGGGDRGYGGGERSYGGGDRSYGGGGGGYSNRSGGYSSGGGYRDNRNQ-GGY-DR-SG 192

Human   158 GSYRDSYDSYGKSH 171
            |||||.||||. ||
Zfish   193 GSYRDGYDSYA-SH 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CIRBPNP_001287758.1 RRM <3..>90 CDD:223796 65/86 (76%)
RRM_CIRBP_RBM3 6..85 CDD:240895 60/78 (77%)
cirbpbNP_001035411.2 RRM <2..>81 CDD:223796 61/78 (78%)
RRM_SF 5..83 CDD:302621 59/77 (77%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 112 1.000 Domainoid score I23809
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 197 1.000 Inparanoid score I11056
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG43500
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000446
OrthoInspector 1 1.000 - - otm28540
orthoMCL 1 0.900 - - OOG6_100265
Panther 1 1.100 - - LDO PTHR48034
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X860
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 1 1.500 - -
1212.470

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