Protein Alignment CIRBP and SC35

DIOPT Version :10

• Sequence 1: NP_001287758.1
• Gene: CIRBP / 1153
• HGNCID: 1982
• Length: 297
• Species: Homo sapiens
• Sequence 2: NP_652612.1
• Gene: SC35 / 53444
• FlyBaseID: FBgn0265298
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 169
• Identity: 62/169 - (36%)
• Similarity: 87/169 - (51%)
• Gaps: 24/169 - (14%)

Human     8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSV 72
            |.|..|::.|..:.|.:||.:.|::.::.:.:||.|:.||||.||.|.:..||:||:.||:|:.:
  Fly    25 LKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDAEDALEAMDGRML 89

Human    73 DGRQIRVDQA--GK-SSDNRSRGYRGGSAGGRGFFRGGRGRGRG------FSRGGGDRGYGGNRF 128
            |||::||..|  |: ||..||...|.|..||.|  .|||.|.|.      .||....|.|..:|.
  Fly    90 DGRELRVQMARYGRPSSPTRSSSGRRGGGGGGG--SGGRRRSRSRSPMRRRSRSPRRRSYSRSRS 152

Human   129 E-----------SRSGGYGGSRDYYSSRSQSGGYSDRSS 156
            .           |||...|.||:  ...|.|||.:..:|
  Fly   153 PGSHSPERRSKFSRSPVRGDSRN--GIGSGSGGLAPAAS 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CIRBP	NP_001287758.1	RRM_CIRBP_RBM3	6..85	CDD:409883	32/79 (41%)
SC35	NP_652612.1	RRM_SRSF2_SRSF8	25..97	CDD:409751	29/71 (41%)