Protein Alignment CIRBP and eIF4B

DIOPT Version :10

• Sequence 1: NP_001287758.1
• Gene: CIRBP / 1153
• HGNCID: 1982
• Length: 297
• Species: Homo sapiens
• Sequence 2: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 167
• Identity: 48/167 - (28%)
• Similarity: 72/167 - (43%)
• Gaps: 33/167 - (19%)

Human     9 FVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVD 73
            ::..|.||.||..|.:.|.....||..:..:|.|..||||||:|..||.:|... ::::...|:.
  Fly    83 YINNLPFDANEDDLYEFFEGINLISLRLPREDGENGRSRGFGYVELENREDLIH-VLSLPDPSIK 146

Human    74 GRQIRV------DQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNRFESRS 132
            ||:||:      ||..:...||                    |..||...|.:|..|..|.:|::
  Fly   147 GRRIRIELSNENDQQSRQKSNR--------------------RFDGFGNNGDNRDSGNWRRDSQN 191

Human   133 GG--YGGS----RDYYSSRSQSGGYSDRSSGGSYRDS 163
            .|  :|.|    |.:...|.......|.::.||:|.|
  Fly   192 NGSNFGYSSNFERSFNRERKSLPDRDDVNTPGSWRTS 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CIRBP	NP_001287758.1	RRM_CIRBP_RBM3	6..85	CDD:409883	28/81 (35%)
eIF4B	NP_001015319.1	RRM_eIF4B	78..159	CDD:409836	26/76 (34%)