Protein Alignment CIRBP and hrpa-2

DIOPT Version :9

• Sequence 1: NP_001287758.1
• Gene: CIRBP / 1153
• HGNCID: 1982
• Length: 297
• Species: Homo sapiens
• Sequence 2: NP_741783.1
• Gene: hrpa-2 / 180791
• WormBaseID: WBGene00019249
• Length: 336
• Species: Caenorhabditis elegans
• Alignment Length: 249
• Identity: 66/249 - (26%)
• Similarity: 97/249 - (38%)
• Gaps: 79/249 - (31%)

Human     7 KLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAM----MAM 67
            |||:||||.||.::.|...||::|.:.:.:|::|..|:.|||||||||.:|..|:.||    ..:
 Worm    71 KLFIGGLSHDTTDEQLGNYFSQWGPVVDAIVIRDPNTKHSRGFGFVTFASIFSAESAMNDRPHKL 135

Human    68 NGKSVDG-RQIRVDQAGKS------SDNRSRGYR---GGSAGG-------RGFFRG--------- 106
            .||:||. |.|..:|....      ..:.:.|.:   .|...|       |.:|..
 Worm   136 GGKTVDSKRAIPREQMSSMIPPPFFETDPAPGCKLLLNGITNGVHSVDSLRVYFETFGTLDQVEI 200

Human   107 -GRGRGRGF----SRGGGDRGYGGN---------RFESRSGGYGGSRDYYSSRSQSGGYS----- 152
             |:.||.||    .:...||....|         :.|.|......:...|..|.||..:|
 Worm   201 LGQPRGLGFVIYEDKESADRCLAHNSGRHIVNERKIEVRVFTKHPNGSTYWKRPQSQSHSQRDLF 265

Human   153 -----------DRSSGGSYRDSYD---------SYGKS----------HSEGAT 176
                       ||.|.|:...:.|         :||.:          |.||::
 Worm   266 EQLSQLNLKDGDRKSTGNSSSAADTPQNFDEDSNYGGTTTEDDCNVFEHEEGSS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CIRBP	NP_001287758.1	RRM	<3..>90	CDD:223796	36/93 (39%)
		RRM_CIRBP_RBM3	6..85	CDD:240895	36/82 (44%)
hrpa-2	NP_741783.1	RRM	<62..230	CDD:223796	49/158 (31%)
		RRM1_hnRNPA_like	71..148	CDD:241022	35/76 (46%)
		RRM_SF	183..240	CDD:302621	11/56 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000446
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000