Protein Alignment CIRBP and rsp-8

DIOPT Version :9

• Sequence 1: NP_001287758.1
• Gene: CIRBP / 1153
• HGNCID: 1982
• Length: 297
• Species: Homo sapiens
• Sequence 2: NP_001255142.1
• Gene: rsp-8 / 176613
• WormBaseID: WBGene00004705
• Length: 309
• Species: Caenorhabditis elegans
• Alignment Length: 226
• Identity: 76/226 - (33%)
• Similarity: 99/226 - (43%)
• Gaps: 61/226 - (26%)

Human     8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSV 72
            |.|..||..|.|:.|..||.::|:|::..:|.||.:..||||||:.|..|:||..|...:....:
 Worm    78 LGVFNLSSYTTEKDLRDVFGEFGEINKCDLVYDRPSGNSRGFGFIYFNLIEDATAARDKLCNTDL 142

Human    73 DGRQIRVD-------------------QAGKSSDN-----------RSRGYRGGSAGGRGFFRGG 107
            ||.:||||                   :.|.||..           ..||.|||...| |..|||
 Worm   143 DGHKIRVDFSLTKRGHSPTPGQYMGDRRGGGSSGGGRFGGGGGDRFNDRGSRGGDRYG-GDRRGG 206

Human   108 RGRGRG--FSRGGGDRGYGGNRF---------ESRSGGY---GGSRDYYSSRSQSGG-------Y 151
            .|.|.|  :..||||| |||:|:         ..|.||:   ||...|..|....||       .
 Worm   207 GGGGGGDRYGGGGGDR-YGGDRYGGGGGRRGSPDRRGGFRSGGGGGGYMRSGGGGGGPDRRDHRD 270

Human   152 SDRSSGG--------SYRDSYDSYGKSHSEG 174
            :||:.||        |:|...:|||..:|.|
 Worm   271 NDRNGGGGGHRPYDPSFRRRVESYGSGNSGG 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CIRBP	NP_001287758.1	RRM	<3..>90	CDD:223796	34/111 (31%)
		RRM_CIRBP_RBM3	6..85	CDD:240895	32/95 (34%)
rsp-8	NP_001255142.1	RRM_TRA2	77..154	CDD:240809	31/75 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I6299
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48034
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010