DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CIRBP and Cirbp

DIOPT Version :9

Sequence 1:	NP_001287758.1	Gene:	CIRBP / 1153	HGNCID:	1982	Length:	297	Species:	Homo sapiens
Sequence 2:	NP_001366350.1	Gene:	Cirbp / 12696	MGIID:	893588	Length:	176	Species:	Mus musculus

Alignment Length:	175	Identity:	164/175 - (93%)
Similarity:	167/175 - (95%)	Gaps:	0/175 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMM 65
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMM 65

Human    66 AMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNRFES 130
            |||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||.||||
Mouse    66 AMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRSRGRGFSRGGGDRGYGGGRFES 130

Human   131 RSGGYGGSRDYYSSRSQSGGYSDRSSGGSYRDSYDSYGKSHSEGA 175
            ||||||||||||:||||.|.|..|||||||||||||||||.|:.|
Mouse   131 RSGGYGGSRDYYASRSQGGSYGYRSSGGSYRDSYDSYGKSSSKDA 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CIRBP	NP_001287758.1	RRM	<3..>90	CDD:223796	85/86 (99%)
CIRBP	NP_001287758.1	RRM_CIRBP_RBM3	6..85	CDD:240895	77/78 (99%)
Cirbp	NP_001366350.1	RRM_CIRBP_RBM3	6..85	CDD:409883	77/78 (99%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83972869
Domainoid	1	1.000	186	1.000	Domainoid score	I27464
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H980
Inparanoid	1	1.050	336	1.000	Inparanoid score	I14653
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S1239
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG43500
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000446
OrthoInspector	1	1.000	-	-		oto119143
orthoMCL	1	0.900	-	-		OOG6_100265
Panther	1	1.100	-	-	LDO	PTHR48034
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X860
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.350