Protein Alignment CKB and Argk2

DIOPT Version :10

• Sequence 1: NP_001349460.1
• Gene: CKB / 1152
• HGNCID: 1991
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_648284.1
• Gene: Argk2 / 39040
• FlyBaseID: FBgn0035957
• Length: 388
• Species: Drosophila melanogaster
• Alignment Length: 363
• Identity: 143/363 - (39%)
• Similarity: 212/363 - (58%)
• Gaps: 39/363 - (10%)

Human    30 MAKVLTPELYAELRAKSTPS-GFTLDDVIQTGVDNPGHPYIMTVGCVAGDEESYEVFKDLFDPII 93
            :.|.||.|::.:|:.|:||| ..||...|.:|:.|    :...||..|.|.|:|:||.|||||:|
  Fly    55 LKKHLTKEIFEKLKTKTTPSFNSTLLHCISSGMCN----HDSGVGLYAPDPEAYKVFADLFDPVI 115

Human    94 EDRHGGYKPSDEHKTDLNPDNLQVRGCGRAGRAGPGSSGAHSRLASQGGDDLDP--NYVLSSRVR 156
            |:.|..:|     |||..|          |...|.|:.          .::|||  ::::|:|||
  Fly   116 EEYHKCFK-----KTDKQP----------ATAFGKGAD----------FENLDPDGHFIVSTRVR 155

Human   157 TGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKP 221
            .||:::|:...|..:..:...:|.....|::||.|:..|:|..|..|.:..|:|||:||:|| |.
  Fly   156 CGRAVKGYPFNPCLTEADYMELESKICGAVTSLTGEYKGKYMPLTGMDKCIQEQLIEDHYLF-KE 219

Human   222 VSPLLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISMQKGGNMKEVFTRFCTGLTQIET 286
            ....|.::|.:|.||..|||:.|..|.||||.|||||:|:|||:|||::.:|:.|...|   :|.
  Fly   220 GDRFLASAGASRYWPTGRGIFLNSAKNFLVWCNEEDHIRIISMEKGGDLGKVYDRMVGG---VEA 281

Human   287 LFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNL-GKHEKFSEVLKRLRLQKRGTGGVD 350
            |  .|..:|..:..||::..||:||||.:||.|||||||| ...::..::..:.|||.|||.|..
  Fly   282 L--GKQLQFNRDERLGFLTFCPTNLGTSIRASVHIKLPNLMCDPDEMKKLADKYRLQIRGTSGEH 344

Human   351 TAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEME 388
            :.|.|||.|:||..|:|.:|.|:::.:.||:|.|||.|
  Fly   345 SEAKGGVHDISNQRRMGLTEYEIIKEMHDGIKGLIEAE 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CKB	NP_001349460.1	creatine_kinase_like	16..397	CDD:153076	143/363 (39%)
Argk2	NP_648284.1	arginine_kinase_like	40..382	CDD:153079	142/361 (39%)