Protein Alignment Acvr2b and put

DIOPT Version :10

• Sequence 1: XP_036010460.1
• Gene: Acvr2b / 11481
• MGIID: 87912
• Length: 557
• Species: Mus musculus
• Sequence 2: NP_001262575.1
• Gene: put / 41772
• FlyBaseID: FBgn0003169
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 239/511 - (46%)
• Similarity: 322/511 - (63%)
• Gaps: 48/511 - (9%)

Mouse    49 ECIYYNANWELERTNQ---SGLERCEGEQDKRLHCYASW--RNSSGTIELVKKGCWLDDFNCYDR 108
            ||.:::.  ::..|.|   :.:|.|:.|.||...||..|  ..::|.:.:..|||:.|...| ::
  Fly    35 ECEHFDE--KMCNTTQQCETRIEHCKMEADKFPSCYVLWSVNETTGILRIKMKGCFTDMHEC-NQ 96

Mouse   109 QECVATEENPQ--VYFCCCEGNFC--NERFTHLPEPGGPEVTYEPPPTAPTLLTV-LAYSLLPIG 168
            .|||.:.|..|  ::||||:|:.|  |:::.........:|..|.......|:.: :..|:..:
  Fly    97 TECVTSAEPRQGNIHFCCCKGSRCNSNQKYIKSTTEATTQVPKEKTQDGSNLIYIYIGTSVFSV- 160

Mouse   169 GLSLIVLLAFWMYRHRKPPYGHVDIHEVRQCQRWAGRRDGCADSFKPLPFQDPGPPPPSPLVGLK 233
             |.:||.:...:||.||..:                        |..:|..:......|||:..:
  Fly   161 -LMVIVGMGLLLYRRRKQAH------------------------FNEIPTHEAEITNSSPLLSNR 200

Mouse   234 PLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKR 298
            |:||||.||.||||.||:|:|.|..||||||.:|:|:||.:|.:|:..|.|:|.|:|:|:..||.
  Fly   201 PIQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKH 265

Mouse   299 GSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIA 363
            ..  :.|.|||:.:...|||.||||.:.|:|.|||.:||:|:.||::|||::|..:.:|.|||||
  Fly   266 MD--KPEYWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIA 328

Mouse   364 HRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLR 428
            |||||||||||||||||.:||||||:.|:||||.||||||||||||||||||||||||.||||||
  Fly   329 HRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEVLEGAINFNRDAFLR 393

Mouse   429 IDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHP 493
            ||:||.||||||:||||..| |||.|:.||||.|:|..|||:|:||.||.||:||.:.:.|..||
  Fly   394 IDVYACGLVLWEMVSRCDFA-GPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHP 457

Mouse   494 GLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVD 549
            ||...|.|:|||||||||||||:.||.||.:    .:|...|..|  |:.:.||:|
  Fly   458 GLNVFCDTMEECWDHDAEARLSSSCVMERFA----QLNKYPSTQL--LIKNHTNID 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acvr2b	XP_036010460.1	TFP_LU_ECD_ACVR2B	47..137	CDD:467152	30/96 (31%)
		STKc_ACVR2b	239..529	CDD:271042	182/289 (63%)
put	NP_001262575.1	TFP_LU_ECD_ACVR2	33..125	CDD:467135	30/92 (33%)
		STKc_ACVR2	206..493	CDD:270955	183/293 (62%)