DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GALNT13 and Pgant9

DIOPT Version :9

Sequence 1:	NP_001363332.1	Gene:	GALNT13 / 114805	HGNCID:	23242	Length:	571	Species:	Homo sapiens
Sequence 2:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster

Alignment Length:	512	Identity:	254/512 - (49%)
Similarity:	336/512 - (65%)	Gaps:	21/512 - (4%)

- Green bases have known domain annotations that are detailed below.

Human    54 QEGPGEMGKAVLIPKDDQEKMKEL----FKINQFNLMASDLIALNRSLPDVRLEGCKTKV-YPDE 113
            :|.|||:||.|.:||:..::||:.    :..|.||...||||:::|:|||.|...||.:. |...
  Fly   143 EENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTN 207

Human   114 LPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVK 178
            ||.|.|:|.||||||:.|||||:||::|||.:|:.::|||||.|:...||..||:|..... .|:
  Fly   208 LPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYP-KVQ 271

Human   179 IIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDD 243
            |||.::|.||||||:.||..:|..|:|:||:|||||.|||||||.||..:..|||||:||||||:
  Fly   272 IIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDE 336

Human   244 TFE--YMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIG 306
            |.|  |.....:..|||:|.|.|.|:|||:||. :|......||.:||||||||||||.:|:.:|
  Fly   337 TLEYHYRDSGGVNVGGFDWNLQFSWHPVPERER-KRHNSTAEPVYSPTMAGGLFSIDREFFDRLG 400

Human   307 TYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEV 371
            |||:|.|||||||||:||:.|.|||:||||.||||||:|||.:||.:..|. :|:.||:.|||||
  Fly   401 TYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGV-NVLKKNSVRLAEV 464

Human   372 WMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIPRRYYSLGEIRNV 436
            ||||:..::| ...|..|.|:||||.|:.||.:||||.|.|||:||||:..||....:.|||||:
  Fly   465 WMDEYSQYYY-HRIGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNL 528

Human   437 --ETNQCLDNMGRKENEK--VGIFNCHGMGGNQVFSYTADKEIRTDDLCLDVSRLNGPVIMLKCH 497
              ....|||....|:::|  ||.:.||..||||.:..:...|||.||.|||.:  ...|.:..||
  Fly   529 GYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRRDDSCLDYA--GKDVTLFGCH 591

Human   498 HMRGNQLWEYDAETHTLLHIITQSCLSVNKVADGSQHPTVETCNDS-TLQKWLLRNY 553
            ..:|||.|.|...|..|.|..:..||::::..|   ...:|.|:.| :.|:|.|.||
  Fly   592 GGKGNQFWTYRENTKQLHHGTSGKCLAISESKD---KLLMEECSASLSRQQWTLENY 645

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GALNT13	NP_001363332.1	pp-GalNAc-T	118..418	CDD:133004	172/301 (57%)
GALNT13	NP_001363332.1	Ricin_B_lectin	431..548	CDD:395527	44/121 (36%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	156/274 (57%)
		pp-GalNAc-T	213..510	CDD:133004	172/300 (57%)
		Ricin_B_lectin	521..640	CDD:279046	44/123 (36%)
		RICIN	523..642	CDD:238092	45/123 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52215
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102903
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.660