Protein Alignment PGLYRP3 and PGRP-LF

DIOPT Version :10

• Sequence 1: XP_011507420.1
• Gene: PGLYRP3 / 114771
• HGNCID: 30014
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_648299.3
• Gene: PGRP-LF / 39064
• FlyBaseID: FBgn0035977
• Length: 369
• Species: Drosophila melanogaster
• Alignment Length: 344
• Identity: 96/344 - (27%)
• Similarity: 151/344 - (43%)
• Gaps: 57/344 - (16%)

Human    42 FVSISQFIHKGRNDTPTIVSRKEW-GARPLACRALLTLPVAYIITDQLPGMQCQQQSVCSQMLRG 105
            |:.:..|.....|....|:.|.|| |..|......|.|||:.||........|:|:.||...::.
  Fly    42 FMWMMSFSTHSPNKGLHILDRSEWLGEPPSGKYPHLKLPVSNIIIHHTATEGCEQEDVCIYRMKT 106

Human   106 LQSHSVYTIGWCDVAYNFLVGDDGRVYEGVGWNIQGLHTQGYNNISLGIAFFGNKIGSSPSPAAL 170
            :|:..:.:.||.|:.||||||.||::|.|.||:|||.|..||..||:.|||.|..:...|....:
  Fly   107 IQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQI 171

Human   171 SAAEGLISYAIQKGHLSPRY-------IQPL-------------------------LLKEETCLD 203
            .||:.|:...::...|.|.|       :.|.                         ||..||.
  Fly   172 EAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQNWPRFTQDPTSLRLLSNETV-- 234

Human   204 PQHPVMPRKVCPNIIKRSAWEARETHCP--KMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQSF 266
                        .|:.|..|.|:....|  .:.||.:.|..:.|...||....:|...||.:|::
  Fly   235 ------------KIVTRPYWLAQPPIVPLTPLKLPIESVRFVATNTPSCFTQAECTFRVRLLQNW 287

Human   267 HMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAAQ 331
            |:::..:.||.|:|:...|..:||..||..........:::.  :||||      |:::..:.|.
  Fly   288 HIESNGYKDINYNFVAAGDENIYEARGWDHSCEPPKDADELV--VAFIG------PSSSNKKIAL 344

Human   332 DLIQCAVVEGYLTPNYLLM 350
            :||:..:..|:::.||.|:
  Fly   345 ELIKQGIKLGHISKNYSLI 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGLYRP3	XP_011507420.1	PGRP	57..195	CDD:128941	52/170 (31%)
		PGRP	215..355	CDD:128941	37/138 (27%)
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	51/141 (36%)
		PGRP	236..363	CDD:470657	36/134 (27%)