Protein Alignment PGLYRP3 and PGRP-LE

DIOPT Version :10

• Sequence 1: XP_011507420.1
• Gene: PGLYRP3 / 114771
• HGNCID: 30014
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_573078.1
• Gene: PGRP-LE / 32534
• FlyBaseID: FBgn0030695
• Length: 345
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 95/305 - (31%)
• Similarity: 152/305 - (49%)
• Gaps: 59/305 - (19%)

Human    94 QQQSVCSQMLRGLQS--HSVYTIGWCDVAYNFLVGDDGRVYEGVGWNIQGLHTQGYNNISLGIAF 156
            ::.|:.|..:|.|.:  :|:.|:|      |..:.:...|:.|...||.|       ||.:
  Fly    69 KKHSIISDTIRDLMNSINSIQTLG------NVNISNSTNVHIGNVTNING-------NIQI---- 116

Human   157 FGNKIGSSPSPAALSAAEGLISYAIQKGHLS-PRYIQPLL---------------LKEETCLDPQ 205
                           .|:||......:.|:| ||...|..               ::.:..:..|
  Fly   117 ---------------IADGLTQNRRDRRHVSPPRDNAPKTPTHFEDDYQDESEERVRSDVFIRRQ 166

Human   206 HPVMPRKVCPNIIKRSAWEARETHCP-----KMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQS 265
            ...:|:::.. ||.||:|.|::   |     .:.||.|||:|:|||..|.........::|::|.
  Fly   167 KFKIPKELSA-IIPRSSWLAQK---PMDEPLPLQLPVKYVVILHTATESSEKRAINVRLIRDMQC 227

Human   266 FHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAA 330
            ||:::|.:.||.|:||||.||.:|||.||...|:||.|:|.|:|||:|||.|:::.|.|.||...
  Fly   228 FHIESRGWNDIAYNFLVGCDGNIYEGRGWKTVGAHTLGYNRISLGISFIGCFMKELPTADALNMC 292

Human   331 QDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQALYNIISTWPHF 375
            ::|:...|.:|:::.:|.|:.|....:..|||:.||..|.|||||
  Fly   293 RNLLARGVEDGHISTDYRLICHCQCNSTESPGRRLYEEIQTWPHF 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGLYRP3	XP_011507420.1	PGRP	57..195	CDD:128941	23/103 (22%)
		PGRP	215..355	CDD:128941	59/144 (41%)
PGRP-LE	NP_573078.1	PGRP	175..317	CDD:128941	59/145 (41%)