Protein Alignment CHUK and Y39G8B.5

DIOPT Version :9

• Sequence 1: XP_016871100.1
• Gene: CHUK / 1147
• HGNCID: 1974
• Length: 814
• Species: Homo sapiens
• Sequence 2: NP_496929.2
• Gene: Y39G8B.5 / 189764
• WormBaseID: WBGene00012726
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 742
• Identity: 159/742 - (21%)
• Similarity: 278/742 - (37%)
• Gaps: 190/742 - (25%)

Human    19 ERLGTGGFGNVCLYQHR-ELDLKIAIKSCRLELSTK-NRERWCHEIQIMKKLNH-ANVV-----K 75
            |.:..|.:..|  |:.| |....:|:|:.|...|.| :.:..|.||.|:|||.. ||:|     |
 Worm    25 EFMAKGAYSQV--YRGRTESGRLVAVKTARKTASNKADVDAMCTEIDILKKLKGVANIVQYFGSK 87

Human    76 ACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKI 140
            ...:|.. ::.|..:. .||| |:...|...:.:|||..||..:.::.|:.|....:..|.|:.|
 Worm    88 NTKIPPG-SVTIETIS-FAME-CASRSLDAEMRRPENHKGLPSNVLIDLVVDCSMALSALREHNI 149

Human   141 IHRDLKPENIVL----QDVGGKIIH--KIIDLGYAKDVDQGSL--CTSFVGTLQYLAPELF---- 193
            .|||:|..||:|    ...|.:..|  |:.|:|.:|.:.:.|.  ..|..||..:|.|:..
 Worm   150 AHRDIKHMNILLFPGSPTRGRRSTHLFKLCDMGCSKAISENSSQELNSIAGTKTFLYPDHIPPNG 214

Human   194 ----ENKPYT-ATVDYWSFGTMVFECIAGYRPF--------LHHL-------------------- 225
                ....|| ...|.||.|..::.|..|..||        |:|:
 Worm   215 HNWKTKSAYTPEQCDLWSLGCTLYFCATGEFPFESTRADANLYHMAAVDLTRNPNAVAVNLVQVE 279

Human   226 QPFTWHEKIKKKDPKCIFACEEMSGE-VRFSSHLPQPNSLCSLVV-------EP-MENWLQ---L 278
            .|.| .||:...:|     ..|:..| .|:...|     :|::..       || :|.:.:   :
 Worm   280 NPVT-KEKVFNFEP-----VTELPAEFTRYPKWL-----VCTMTCLLRNFFHEPSIEYYAKVAGV 333

Human   279 MLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKI------------ISFLLPPD 331
            |.|              .:.|.|..:|.:..::...:.|:..:.:            |..:|..:
 Worm   334 MRN--------------SKRRTFASVDQMSIVEHTDMSNILESSLPSISECLGYPEGIDIVLLAN 384

Human   332 ESLHSLQSRIERETGINTGSQELLSETG-------ISLDPRKPASQCVLD------GVRGC---- 379
            .|.|.|.|:.:...|:......:|.:|.       :..:.:....:|:.|      .::.|
 Worm   385 TSTHYLDSKQKSVDGLPDDLYLVLPQTSQVEMRTLLKRNIKFNELECMTDTKLIEIRIKKCYEGL 449

Human   380 ------DSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLK 438
                  |.|: .|||:         .|..||...:.:||:.. |...:|....:|..|...|
 Worm   450 SMLTEVDEYL-DLFDR---------VSAILSTQFSLLVQELS-QFERVQTTSRFAVYVDMAS--- 500

Human   439 EDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGIS 503
                       ..|:.....|.....:.:..|..:.|.:.:|| .|..:.:|.|..:::::
 Worm   501 -----------VPMMLFDEANPEAKTIADQCIQQAIQAREELE-RHAKVAMDFEACAKKLS---- 549

Human   504 SEKMLKAWKEMEEKAIHYAEV-GVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDL 567
                    :|.|:..:...:: |:...:|..:....|.|:..||  |.:   :|:|...:|...:
 Worm   550 --------REAEDLRLEDMDLPGIRREIESYLFYDKATILSTQK--YTQ---ELVELCLKRRNTV 601

Human   568 YKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPK-VEVALSN 631
            .||:.:.|      |.....|:  :|..:....|.:|.....||.....:.:|||.| .:|...|
 Worm   602 MKQIFNSP------DGINKSKL--NTAMNLAASLSQLRSDYQKLQDMISECVDLLEKPFQVMKDN 658

Human   632 IKEADNTVMFMQG---KRQKEIWHLLK 655
            :    |..:..||   ...::..|||:
 Worm   659 V----NRYLQAQGCSRNTMEKSMHLLR 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHUK	XP_016871100.1	None
Y39G8B.5	NP_496929.2	PKc_like	25..263	CDD:389743	70/242 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4250
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810