Protein Alignment ERMAP and fred

DIOPT Version :9

• Sequence 1: NP_001017922.1
• Gene: ERMAP / 114625
• HGNCID: 15743
• Length: 475
• Species: Homo sapiens
• Sequence 2: NP_608812.3
• Gene: fred / 33613
• FlyBaseID: FBgn0051774
• Length: 1447
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 89/468 - (19%)
• Similarity: 143/468 - (30%)
• Gaps: 193/468 - (41%)

Human    17 PLVFLRLSVHVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVPKEVRWLRSPFPQRSQAVHIFR 81
            |:||:.            .|.|.|..|.|..:.|.::..|.  |..|.||:...|.       ||
  Fly   317 PIVFIE------------SKTHEAEEGETVLIRCNVTANPS--PINVEWLKEGAPD-------FR 360

Human    82 DGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLEDQGSYRCLIQVGNLSKEDTVILQVAAP 146
                        |.|..:.:     ||       ||.|..|:|.|        :...::...::.
  Fly   361 ------------YTGELLTL-----GS-------VRAEHAGNYIC--------RSVNIMQPFSSK 393

Human   147 SVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQRRAKEKLLYEHVTEVDNLLSDHAKEKGKLHKA 211
            .|..:..|.|||.|                 :.|..:     .::|.               :|.
  Fly   394 RVEGVGNSTVALLV-----------------RHRPGQ-----AYITP---------------NKP 421

Human   212 VKKLRSELKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRF 276
            |..:.:.:.|..:|...||...:..:.. .:|.|..:.:.||::                .|| :
  Fly   422 VVHVGNGVTLTCSANPPGWPVPQYRWFR-DMDGDIGNTQKILAQ----------------GPQ-Y 468

Human   277 DFVVSILGSE--YFTTGCH-YWEVYVGDKTKWILGV----------------------CSESVSR 316
            ....:.||||  |.   || ..|:.:|.....||.|                      .:.:.|.
  Fly   469 SIPKAHLGSEGKYH---CHAVNELGIGKIATIILEVHQPPQFLAKLQQHMTRRVGDVDYAVTCSA 530

Human   317 KGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIF 381
            |||.|...   .|:   ..|.|   :...:..|.::..|...|      .||::..::.
  Fly   531 KGKPTPQI---RWI---KDGTE---ILPTRKMFDIRTTPTDAG------GGVVAVQSIL------ 574

Human   382 TFTHNFSGPLRP----------FFEPCLHDGGKNTA-----------PLVI------CSELHKSE 419
                .|.|..||          ....||::...|:|           |:||      ..:|.:|.
  Fly   575 ----RFRGKARPNGNQLLPNDRGLYTCLYENDVNSANSSMHLRIEHEPIVIHQYNKVAYDLRESA 635

Human   420 ESI-----VPRPE 427
            |.:     .|:||
  Fly   636 EVVCRVQAYPKPE 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERMAP	NP_001017922.1	Ig	43..144	CDD:325142	21/100 (21%)
		SPRY_PRY_TRIM20	230..412	CDD:293985	43/233 (18%)
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653
		Ig	147..228	CDD:299845
		I-set	232..313	CDD:254352
		IGc2	250..302	CDD:197706
		IG_like	323..385	CDD:214653	24/102 (24%)
		IGc2	330..385	CDD:197706	21/95 (22%)
		Ig_2	416..501	CDD:290606	24/120 (20%)
		IG_like	418..501	CDD:214653	23/118 (19%)
		I-set	505..612	CDD:254352	21/131 (16%)
		Ig	526..611	CDD:143165	21/109 (19%)
		IG_like	633..715	CDD:214653	5/16 (31%)
		Ig	635..713	CDD:143165	4/14 (29%)
		FN3	720..838	CDD:238020

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910