DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment angptl3 and CG31832

DIOPT Version :9

Sequence 1:	NP_571893.2	Gene:	angptl3 / 114421	ZFINID:	ZDB-GENE-010817-3	Length:	466	Species:	Danio rerio
Sequence 2:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster

Alignment Length:	218	Identity:	74/218 - (33%)
Similarity:	109/218 - (50%)	Gaps:	19/218 - (8%)

- Green bases have known domain annotations that are detailed below.

Zfish   256 VFTRGQKT---------SGIYPIKPNQSEPFYV-YCEITPDGAATVIQRREDGSVDFDQSWEKYE 310
            :|..||.:         :||:.:...:.|||.| .|:.|... ..|||||.||||:|:|||..|:
  Fly    14 LFEVGQSSPHTCPSGSPNGIHQLMLPEEEPFQVTQCKTTARD-WIVIQRRLDGSVNFNQSWFSYK 77

Zfish   311 HGFGKLEKEFWLGLAKIHSIAQQGEYILHIELEDWKEEKRFIEY-TFTLEGPASDYAL-HLAPLS 373
            .|||....||::||.|::.:.::..:.|.|:|:.......:..: .|.::.....|.| .:...|
  Fly    78 DGFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYS 142

Zfish   374 GDLSDAMSNHTGMKFSTKDRDNDNHDESNCARNYTGGWWFDACGDTNLNGRYAWMRSKARHQRRK 438
            |...|::..|...:|||.||||| ....|||..:.|||||.:|..::|||.|.   .:.......
  Fly   143 GTAGDSLRYHINKRFSTFDRDND-ESSKNCAAEHGGGWWFHSCLSSSLNGLYF---REGETGMLN 203

Zfish   439 GIYWRPSKGSSYTLKSTKITIRP 461
            ||:|...|..|.|.  .:|.|||
  Fly   204 GIHWGRWKFQSLTF--VQIMIRP 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
angptl3	NP_571893.2	SMC_N	<111..>209	CDD:330553
angptl3	NP_571893.2	FReD	248..461	CDD:238040	72/216 (33%)
CG31832	NP_723894.2	FReD	28..225	CDD:238040	71/204 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900