DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment angpt2b and CG31832

DIOPT Version :9

Sequence 1:	NP_571889.1	Gene:	angpt2b / 114408	ZFINID:	ZDB-GENE-010817-2	Length:	489	Species:	Danio rerio
Sequence 2:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster

Alignment Length:	204	Identity:	83/204 - (40%)
Similarity:	112/204 - (54%)	Gaps:	9/204 - (4%)

- Green bases have known domain annotations that are detailed below.

Zfish   288 NGIYSIHLPNSTQKIKVFCDMKTKGGGWTVFQHRYDGSVDFNRDWNDYKLGFGDPSGEHWLGNDV 352
            |||:.:.||.........|  ||....|.|.|.|.||||:||:.|..||.|||||:||.::|...
  Fly    31 NGIHQLMLPEEEPFQVTQC--KTTARDWIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFIGLQK 93

Zfish   353 IHLLTTTKDYTLQVHLKDAEEHQAYSQYDTFYIDGEDKKYSLHARG-FSGTAGRTSSLTHSGTQF 416
            ::|:|..:.:.|.:.||.......|:.:|.|.:|.|.:.|.|...| :||||| .|...|...:|
  Fly    94 LYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSGTAG-DSLRYHINKRF 157

Zfish   417 STKDQDNDQCSCKCAQMATGGWWFEACGPSNLNGIYY-SGNSNVIRYNSIKWYYWKGPSWMATMT 480
            ||.|:|||:.|..||....|||||.:|..|:|||:|: .|.:.::  |.|.|..||..|  .|..
  Fly   158 STFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYFREGETGML--NGIHWGRWKFQS--LTFV 218

Zfish   481 TMMIRPVDF 489
            .:||||..|
  Fly   219 QIMIRPKYF 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
angpt2b	NP_571889.1	NYD-SP28	164..244	CDD:291438
angpt2b	NP_571889.1	FReD	274..487	CDD:238040	81/200 (41%)
CG31832	NP_723894.2	FReD	28..225	CDD:238040	81/200 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810