DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RNF13 and DMA1

DIOPT Version :9

Sequence 1:	NP_001365214.1	Gene:	RNF13 / 11342	HGNCID:	10057	Length:	381	Species:	Homo sapiens
Sequence 2:	NP_011983.1	Gene:	DMA1 / 856515	SGDID:	S000001157	Length:	416	Species:	Saccharomyces cerevisiae

Alignment Length:	151	Identity:	34/151 - (22%)
Similarity:	60/151 - (39%)	Gaps:	48/151 - (31%)

- Green bases have known domain annotations that are detailed below.

Human   212 RARRNRLRKDQLKKLP-VHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPW--LTK 273
            :.:.|...|:.|.::. :.|...|.|.:.|:|||::.:....:.|.||:|::|..||...  :..
Yeast   298 KLKANAFNKEALSRIKNLQKLTTGLEQEDCSICLNKIKPCQAIFISPCAHSWHFHCVRRLVIMNY 362

Human   274 TKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTES 338
            .:..||.|:         ::.|.:::.|                         |||.|
Yeast   363 PQFMCPNCR---------TNCDLETTLE-------------------------SESES------- 386

Human   339 SDYEEDDNEDTDSSDAENEIN 359
                |.:|||.|..|.|.:|:
Yeast   387 ----EFENEDEDEPDIEMDID 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RNF13	NP_001365214.1	PA_C_RZF_like	23..180	CDD:239038
		RING-H2_RNF167	238..283	CDD:319711	14/46 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..381		14/75 (19%)
DMA1	NP_011983.1	FHA	121..308	CDD:224630	2/9 (22%)
DMA1	NP_011983.1	RING-H2_Dmap_like	325..371	CDD:319372	13/45 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000