Protein Alignment RNF13 and HRD1

DIOPT Version :9

• Sequence 1: NP_001365214.1
• Gene: RNF13 / 11342
• HGNCID: 10057
• Length: 381
• Species: Homo sapiens
• Sequence 2: NP_014630.1
• Gene: HRD1 / 854149
• SGDID: S000005373
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 516
• Identity: 104/516 - (20%)
• Similarity: 174/516 - (33%)
• Gaps: 191/516 - (37%)

Human     1 MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLP------------- 52
            |:||| .::|::|.::.:||..||..|.|:..|            ..|:.||
Yeast    49 MVLSI-FILLNSTLLWQLLTKLLFGELRLIEHE------------HIFERLPFTIINTLFMSSLF 100

Human    53 --------ARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLI-RRLDCNFD-IK 107
                    |.||..|....:..:::..:.|...:.|       |.|.|...|| .|...|.. :.
Yeast   101 HERYFFTVAFFGLLLLYLKVFHWILKDRLEALLQSI-------NDSTTMKTLIFSRFSFNLVLLA 158

Human   108 VLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLK----KIDIPSVFI------------------ 150
            |::.|......:.::.....|:.|.....|:|::    .||:.::|:
Yeast   159 VVDYQIITRCISSIYTNQKSDIESTSLYLIQVMEFTMLLIDLLNLFLQTCLNFWEFYRSQQSLSN 223

Human   151 -----------GESSANS----------------------LKDEFTYEK-----------GGHLI 171
                       .|::..|                      |:.:|.|||           ..||.
Yeast   224 ENNHIVHGDPTDENTVESDQSQPVLNDDDDDDDDDRQFTGLEGKFMYEKAIDVFTRFLKTALHLS 288

Human   172 LVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRA----RRNRLRKDQLKKLPVHKFK 232
            ::..|.:|:             .|:..|::.|....|.....    |.|:...|.|..:.|.:.:
Yeast   289 MLIPFRMPM-------------MLLKDVVWDILALYQSGTSLWKIWRNNKQLDDTLVTVTVEQLQ 340

Human   233 -KGDEYDVCAICLDEY----------EDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVV 286
             ..::.::|.||:||.          ....|.:.|||.|..|..|:..|:.:: :|||:|:..|.
Yeast   341 NSANDDNICIICMDELIHSPNQQTWKNKNKKPKRLPCGHILHLSCLKNWMERS-QTCPICRLPVF 404

Human   287 PSQGD-------SDSD--------------TDSSQEENEV----TEHT-PLLRPLASVSAQSFGA 325
            ..:|:       |:||              ||.....|||    |..| |.:|   .|..|:...
Yeast   405 DEKGNVVQTTFTSNSDITTQTTVTDSTGIATDQQGFANEVDLLPTRTTSPDIR---IVPTQNIDT 466

Human   326 LSESRSHQNMTESSD------YEEDDNE-----------DTDSSDAEN------EINEHDV 363
            |: .|:....|.|..      ::..||.           .|:|.:.||      .|..|:|
Yeast   467 LA-MRTRSTSTPSPTWYTFPLHKTGDNSVGSSRSAYEFLITNSDEKENGIPVKLTIENHEV 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF13	NP_001365214.1	PA_C_RZF_like	23..180	CDD:239038	40/245 (16%)
		RING-H2_RNF167	238..283	CDD:319711	17/54 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..381		29/128 (23%)
HRD1	NP_014630.1	HRD1	5..551	CDD:227568	104/516 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910