Protein Alignment RNF13 and C18B12.4

DIOPT Version :9

• Sequence 1: NP_001365214.1
• Gene: RNF13 / 11342
• HGNCID: 10057
• Length: 381
• Species: Homo sapiens
• Sequence 2: NP_510498.1
• Gene: C18B12.4 / 181600
• WormBaseID: WBGene00007666
• Length: 456
• Species: Caenorhabditis elegans
• Alignment Length: 366
• Identity: 98/366 - (26%)
• Similarity: 160/366 - (43%)
• Gaps: 64/366 - (17%)

Human    69 INSKPENACEPIVPPPVKDNSSGTFIVLIRRLD----CNFDIKVLNAQRAGY--KAAIVHNVDSD 127
            :..:|.:||.|:................:.|.:    |.|..:....|.:.|  :..|.:|....
 Worm    71 VGVEPVDACGPVRIAQNHTTRCHNLFAFVSRSNISHPCKFSHQAFMVQNSTYPFRLVIFYNYPGQ 135

Human   128 DLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHL-ILVPEFSLPLEYYLIPFLIIV 191
            :.|||  ...|:..|::||.:.|..:....:..:|:...|..| :.:......|..||||||:::
 Worm   136 EPISM--EGTELRDKVNIPVLMISHACKEEIAKKFSDTAGYRLRVRIDPGYYELFRYLIPFLVVI 198

Human   192 GICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRIL 256
            ..|..|.:|.:..:...:|.:..:.||.|..|||:||.|::.||:.|.|||||:.:..|:|||.|
 Worm   199 VFCFALFLITLCVRGCVERRKLNKRRLSKRNLKKIPVKKYRLGDDPDTCAICLESFASGEKLRHL 263

Human   257 PCSHAYHCKCVDPWLTKTKKTCPVCKQKV--------------VPSQGDSDS------------- 294
            ||.|.:||.|:|.|||:|:|.||:||:|:              ..|||.:|:
 Worm   264 PCRHVFHCNCIDVWLTQTRKICPLCKRKIGTDSDSECSTNDLASTSQGPNDATALYNNADNQSGF 328

Human   295 ----------DTDSSQE---ENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDD- 345
                      |..||||   :.::..|....|.:......:|..|..|..|:::...|..|...
 Worm   329 ELPVPQGQMVDLWSSQEALVDQDIVLHNTTRRSITGFVRNAFRKLRNSPRHRDVDVHSGLEGGSY 393

Human   346 --NEDTDSSD----AENEINEHDVVVQLQPNGERDYNIANT 380
              .:.|.|:|    .|||:::        |....:.||.::
 Worm   394 LVRQQTTSNDNDHLLENEVSD--------PTSSSELNIPSS 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF13	NP_001365214.1	PA_C_RZF_like	23..180	CDD:239038	22/117 (19%)
		RING-H2_RNF167	238..283	CDD:319711	26/44 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..381		26/143 (18%)
C18B12.4	NP_510498.1	PA	<74..176	CDD:333703	21/103 (20%)
		HRD1	<223..>335	CDD:227568	43/111 (39%)
		RING-H2_RNF103	246..291	CDD:319387	26/44 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I6450
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I3469
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		otm15079
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1776
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.750