Protein Alignment EXOSC8 and Rrp42

DIOPT Version :10

• Sequence 1: NP_852480.1
• Gene: EXOSC8 / 11340
• HGNCID: 17035
• Length: 276
• Species: Homo sapiens
• Sequence 2: NP_725517.2
• Gene: Rrp42 / 36766
• FlyBaseID: FBgn0034065
• Length: 296
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 69/266 - (25%)
• Similarity: 127/266 - (47%)
• Gaps: 9/266 - (3%)

Human    13 YYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKG 77
            |....::::.|.|||...::|...:..|.:|.|.|||.::|.||.::.|||.|...|:...|:.|
  Fly    13 YILHGVEDDFRCDGRSRRDYRPMDLETGLVSNASGSARLRLANTDILVGVKTEIDVPNPLTPEFG 77

Human    78 YVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLICL 142
            .:...||.....:..|......:.||.....:.:..|:........||:.||:..|.||.|::.|
  Fly    78 KLEFFVDCSANATPEFEGRGGSDLAQELILSLQNAYESPLAFNYRTLCLIPGQQCWKLYIDILIL 142

Human   143 DYDGNILDACTFALLAALKNVQLPEVTINE-ETALAEVNLKKKSY----LNIRTHPVATSFAVFD 202
            :..||:.||.:.|..|||.|.:||.||... :..:.::.:....|    :.|.|.|:..:.....
  Fly   143 ECGGNLHDAVSLAAKAALFNTKLPRVTATMLDAGITDLIISDNPYDCTRIGIETVPLLVTVCKIG 207

Human   203 DTLLIVDPTGEEEHLATGTLTI---VMDEEGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVKK 264
            |.:| |||:.|||..:|.::.:   :.:.:..|...|..||..:....:::|:...:...:.:.:
  Fly   208 DYVL-VDPSAEEEVCSTVSMVVSVSMRNGQAFLSGTHLTGGGAMHRDTMRNCLELGLAIGEHLDR 271

Human   265 LMDEVI 270
            |:.:::
  Fly   272 LLTKML 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC8	NP_852480.1	RNase_PH_RRP43	6..266	CDD:206774	68/260 (26%)
Rrp42	NP_725517.2	RNase_PH_RRP42	5..278	CDD:206772	69/266 (26%)