Protein Alignment CBX3 and Su(var)205

DIOPT Version :10

• Sequence 1: NP_009207.2
• Gene: CBX3 / 11335
• HGNCID: 1553
• Length: 183
• Species: Homo sapiens
• Sequence 2: NP_476755.1
• Gene: Su(var)205 / 34119
• FlyBaseID: FBgn0003607
• Length: 206
• Species: Drosophila melanogaster
• Alignment Length: 206
• Identity: 88/206 - (42%)
• Similarity: 123/206 - (59%)
• Gaps: 36/206 - (17%)

Human    11 MGKKQNG--KSKKVEEA--EPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPE 71
            ||||.:.  .|.||.:|  |.||:.|||::||||..|||||:|||||:.:.:||||||.||||.:
  Fly     1 MGKKIDNPESSAKVSDAEEEEEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQD 65

Human    72 LIEAFLNSQK-----AGKEKD---------------------GTKRKSLSDSESDDSKSKKKRDA 110
            ||:.:..|:|     |..:||                     .:||||...:....:|||:..||
  Fly    66 LIQQYEASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDA 130

Human   111 ------ADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYE 169
                  .....||.|||:.|:|:||:|::|.|.||:::|..|:|::|.:..||.|.|::||.|||
  Fly   131 EQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYE 195

Human   170 ERLTWHSCPED 180
            |||:|:|..||
  Fly   196 ERLSWYSDNED 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBX3	NP_009207.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		9/20 (45%)
		CD_HP1gamma_Cbx3	29..78	CDD:349299	30/48 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..125		19/77 (25%)
		CSD_HP1gamma_Cbx3	116..173	CDD:349303	29/56 (52%)
Su(var)205	NP_476755.1	CD_HP1a_insect	24..72	CDD:349300	29/47 (62%)
		CSD_HP1a_insect	146..198	CDD:349305	25/51 (49%)