DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PARK7 and dj-1beta

DIOPT Version :9

Sequence 1:	NP_001116849.1	Gene:	PARK7 / 11315	HGNCID:	16369	Length:	189	Species:	Homo sapiens
Sequence 2:	NP_651825.4	Gene:	dj-1beta / 43652	FlyBaseID:	FBgn0039802	Length:	187	Species:	Drosophila melanogaster

Alignment Length:	186	Identity:	98/186 - (52%)
Similarity:	130/186 - (69%)	Gaps:	4/186 - (2%)

- Green bases have known domain annotations that are detailed below.

Human     3 SKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPY 67
            ||.||||||.||||||.:|..||:||||||||||||.|.:.|:|||||.|.||.||.....: .:
  Fly     2 SKSALVILAPGAEEMEFIIAADVLRRAGIKVTVAGLNGGEAVKCSRDVQILPDTSLAQVASD-KF 65

Human    68 DVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDK 132
            ||||||||..|:..:.||:.|.::|:.||:..||||||||.||.|..|.:..|..:|::|..|.:
  Fly    66 DVVVLPGGLGGSNAMGESSLVGDLLRSQESGGGLIAAICAAPTVLAKHGVASGKSLTSYPSMKPQ 130

Human   133 MMNGGHYTYSENR-VEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVL 187
            ::|  :|:|.::: |.|||.::|||||||::||||.|.|.|.|||...:|...|::
  Fly   131 LVN--NYSYVDDKTVVKDGNLITSRGPGTAYEFALKIAEELAGKEKVQEVAKGLLV 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PARK7	NP_001116849.1	not_thiJ	5..184	CDD:213612	95/179 (53%)
dj-1beta	NP_651825.4	not_thiJ	4..181	CDD:213612	95/179 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147889
Domainoid	1	1.000	171	1.000	Domainoid score	I3745
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38295
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3996
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54253
OrthoDB	1	1.010	-	-		D1165707at2759
OrthoFinder	1	1.000	-	-		FOG0002774
OrthoInspector	1	1.000	-	-		otm42153
orthoMCL	1	0.900	-	-		OOG6_101257
Panther	1	1.100	-	-	LDO	PTHR48094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1763
SonicParanoid	1	1.000	-	-		X2164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.940