Protein Alignment VPS26B and Vps26

DIOPT Version :10

• Sequence 1: NP_443107.1
• Gene: VPS26B / 112936
• HGNCID: 28119
• Length: 336
• Species: Homo sapiens
• Sequence 2: NP_569952.2
• Gene: Vps26 / 31144
• FlyBaseID: FBgn0014411
• Length: 478
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 226/346 - (65%)
• Similarity: 267/346 - (77%)
• Gaps: 24/346 - (6%)

Human     1 MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLALKNPNKRLEHQG 65
            |:|.|||||.::||:.:.|| .|.||.|.||||.||..||||||||||||::.||.|..:|||||
  Fly     1 MNFLGFGQSADIEIVFDGAE-HKTAEVKGEDGKVEKMLLFYDGETVSGKVNVTLKKPGSKLEHQG 64

Human    66 IKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFL 130
            |||||||||||||||||||||..|.|.|||||::.|:.::.|:|..|||.:|.|.|.||:|||||
  Fly    65 IKIEFIGQIELYYDRGNHHEFKCLAKALARPGDLIQNNSYPFDFPKVEKQFEVYAGSNVRLRYFL 129

Human   131 RATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYF 195
            ||||.||::|:.||:||.||||.:|||:|:.||||||||||||||||||||||||:|.|:|||||
  Fly   130 RATIVRRISDITKEVDIAVHTLCSYPEMNNPIKMEVGIEDCLHIEFEYNKSKYHLRDTIIGKIYF 194

Human   196 LLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMR 260
            ||||||||||||.|||:|:|||||.:::||:|||||||||||||:|||||||:|||||.||||||
  Fly   195 LLVRIKIKHMEIAIIKKESTGTGPTMFNENETIAKYEIMDGAPVKGESIPIRVFLAGYNLTPTMR 259

Human   261 DINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVR-------KSMSHQ------------ 306
            ||||||||:|:|||||:|.|:||||||||:.||||.|..|       :...||
  Fly   260 DINKKFSVKYFLNLVLMDTEDRRYFKQQEITLWRKADKPRYHGAQQHQQQQHQHVPLHAPPHLVS 324

Human   307 ----AAIASQRFEGTTSLGEV 323
                ..:|......:|..|||
  Fly   325 GPAAPTVAHSLISSSTDSGEV 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VPS26B	NP_443107.1	Vps26	6..281	CDD:397622	201/274 (73%)
Vps26	NP_569952.2	Vps26	6..280	CDD:397622	201/274 (73%)
		Herpes_BLLF1	<317..>408	CDD:282904	5/29 (17%)