Protein Alignment VPS26B and vps-26

DIOPT Version :10

• Sequence 1: NP_443107.1
• Gene: VPS26B / 112936
• HGNCID: 28119
• Length: 336
• Species: Homo sapiens
• Sequence 2: NP_001263763.1
• Gene: vps-26 / 177764
• WormBaseID: WBGene00006931
• Length: 410
• Species: Caenorhabditis elegans
• Alignment Length: 319
• Identity: 204/319 - (63%)
• Similarity: 258/319 - (80%)
• Gaps: 5/319 - (1%)

Human     4 FGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKI 68
            ||||||.|::|.|::.::||..:.:.:||....:||:||||:|:|.|.:.||..|.:.|||||:|
 Worm    57 FGFGQSAEIQIRLSNEDTRKIVKARGDDGNMHDHFLYYDGESVTGTVHVNLKKANHKFEHQGIRI 121

Human    69 EFIGQI--ELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLR 131
            ||||||  |:||||||..:|:||.::|||||::||:..|.|||.:||||:|:|.|.|||||||||
 Worm   122 EFIGQIVSEVYYDRGNQQDFISLTRELARPGDLTQNAQFPFEFNNVEKPFETYMGTNVKLRYFLR 186

Human   132 ATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFL 196
            .|:.|||.|:.||:|:|||.||:||:.:.||||||||||||||||||||:||||:||||||||||
 Worm   187 VTVIRRLTDLTKELDLVVHALSSYPDNDKSIKMEVGIEDCLHIEFEYNKNKYHLQDVIVGKIYFL 251

Human   197 LVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRD 261
            |||||||:|||.|:|.|..|:|||.:.|::|:||:||||||||||||||||||||||:|.|:|||
 Worm   252 LVRIKIKYMEIAILKTEVVGSGPNTFKESETVAKFEIMDGAPVRGESIPIRLFLAGYDLAPSMRD 316

Human   262 INKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSL 320
            :.|||||:|:|||||:|||:|||||||||.||||.|   |.|........:..:.|||:
 Worm   317 VGKKFSVKYFLNLVLVDEEDRRYFKQQEVTLWRKAD---KVMRRPGTEDDEEEKQTTSI 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VPS26B	NP_443107.1	Vps26	6..281	CDD:397622	182/276 (66%)
vps-26	NP_001263763.1	Vps26	59..336	CDD:397622	182/276 (66%)